COL1A2 Products
(Collagen, Type I, alpha 2 (COL1A2))
Categories
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
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Featured COL1A2 Categories
COL1A2 Antibodies
High quality antibodies with extensive validation data.
COL1A2 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL1A2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL1A2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
- (5)
Cat. No.
ABIN6138839
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
Cat. No.
ABIN6258438
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, ICC, FACS
Validations
- (5)
Cat. No.
ABIN7193541
Quantity
100 μL
Datasheet
Datasheet
Recommended COL1A2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6954918
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954922
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965933
Quantity
96 tests
Datasheet
Datasheet
Recommended COL1A2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122443
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349948
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505087
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our COL1A2 products
: "The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 327, (2021) (PubMed).: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." in: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).
: "A novel hybrid 3D-printed titanium scaffold for osteogenesis in a rabbit calvarial defect model." in: American journal of translational research, Vol. 10, Issue 2, pp. 474-482, (2018) (PubMed).
: "N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force." in: Oncotarget, Vol. 8, Issue 66, pp. 110460-110473, (2017) (PubMed).
: "Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method." in: Experimental hematology, Vol. 44, Issue 11, pp. 1059-1071, (2017) (PubMed).
: "Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC)." in: Journal of proteomics, Vol. 133, pp. 100-12, (2016) (PubMed).
: "Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 12, pp. 4214-4226, (2016) (PubMed).
: "Transportation conditions for prompt use of ex vivo expanded and freshly harvested clinical-grade bone marrow mesenchymal stromal/stem cells for bone regeneration." in: Tissue engineering. Part C, Methods, Vol. 20, Issue 3, pp. 239-51, (2014) (PubMed).
: "Accessibilome of human glioblastoma: collagen-VI-alpha-1 is a new target and a marker of poor outcome." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5660-9, (2014) (PubMed).
: "Inhibition of TGF-? signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine." in: PLoS ONE, Vol. 8, Issue 2, pp. e58000, (2013) (PubMed).
Synonyms and alternative names related to COL1A2
coagulation factor II, thrombin (F2), collagen, type I, alpha 2 (Col1a2), collagen type I alpha 2 chain (Col1a2), collagen type I alpha 2 L homeolog (col1a2.L), collagen type I alpha 2 chain (COL1A2), growth arrest specific 6 (Gas6), collagen, type I, alpha 2 (col1a2), AA960264, AI325291, alpha2(I), Col1a-2, Cola-2, Cola2, Gas-6, hm:zehn2357, OI4, oim, wu:fa98d05, wu:fa99g10, wu:fb04c08, wu:fb11d06, zehn2357Protein level used designations for COL1A2
- prothrombin
- thrombin
- alpha-2 type I collagen
- collagen COL1A2
- collagen alpha-2(I) chain
- osteogenesis imperfecta
- procollagen, type I, alpha 2
- alpha 2(I) collagen
- alpha-2(1) collagen
- collagen alpha 2(I) chain
- alpha 2(I)-collagen
- collagen I, alpha-2 polypeptide
- collagen of skin, tendon and bone, alpha-2 chain
- type I procollagen
- COL1A2 gene exons 8 through 12
- type I procollagen pro-alpha 2 chain
- alpha 2(I) procollagen
- collagen I alpha-2 polypeptide
- AXL receptor tyrosine kinase ligand
- GAS 6
- growth arrest-specific protein 6
- alpha 2 type I collagen
- collagen a2(I)
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