COL1A1 Products
(Collagen, Type I, alpha 1 (COL1A1))
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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
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Featured COL1A1 Categories
COL1A1 Antibodies
High quality antibodies with extensive validation data.
COL1A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL1A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL1A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC, IHC (p), IHC (fro)
Validations
- (74)
- (5)
Cat. No.
ABIN5518708
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7443395
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7431647
Quantity
100 μL
Datasheet
Datasheet
Recommended COL1A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (5)
Cat. No.
ABIN6730967
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962138
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6954914
Quantity
96 tests
Datasheet
Datasheet
Recommended COL1A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349946
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505073
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505045
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our COL1A1 products
: "Lipopolysaccharide induces epithelial-mesenchymal transition of alveolar epithelial cells cocultured with macrophages possibly via the JAK2/STAT3 signaling pathway." in: Human & experimental toxicology, Vol. 39, Issue 2, pp. 224-234, (2020) (PubMed).: "Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis." in: Frontiers in pharmacology, Vol. 11, pp. 200, (2020) (PubMed).
: "Prevention of Diabetic Nephropathy by Modified Acidic Fibroblast Growth Factor." in: Nephron, Vol. 137, Issue 3, pp. 221-236, (2018) (PubMed).
: "Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling." in: Scientific reports, Vol. 7, pp. 43146, (2018) (PubMed).
: "Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation." in: Circulation research, Vol. 122, Issue 8, pp. 1052-1068, (2018) (PubMed).
: "The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).
: "Adiponectin Is Involved in Connective Tissue Growth Factor-Induced Proliferation, Migration and Overproduction of the Extracellular Matrix in Keloid Fibroblasts." in: International journal of molecular sciences, Vol. 18, Issue 5, (2018) (PubMed).
: "Granulocyte-Colony Stimulating Factor (G-CSF) Accelerates Wound Healing in Hemorrhagic Shock Rats by Enhancing Angiogenesis and Attenuating Apoptosis." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 2644-2653, (2018) (PubMed).
: "Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds." in: Disease models & mechanisms, Vol. 10, Issue 9, pp. 1155-1164, (2018) (PubMed).
: "Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4537-4544, (2018) (PubMed).
Synonyms and alternative names related to COL1A1
collagen type I alpha 1 chain (COL1A1), collagen, type I, alpha 1 (Col1a1), collagen type I alpha 1 chain (Col1a1), collagen, type I, alpha 1 S homeolog (col1a1.S), collagen alpha-1(I) chain (LOC397571), collagen type I alpha 2 chain (COL1A2), collagen, type I, alpha 1 (COL1A1), collagen, type I, alpha 1a (col1a1a), collagen 1a1 (col1a1), collagen, type I, alpha 1b (col1a1b), alpha1(I), alpha3(I), cb21, Col1a-1, col1a1, COL1A1, COL1A2, col1a3, Cola-1, Cola1, COLIA1, hm:zeh0348, MGC52532, Mov-13, Mov13, OI4, sb:cb21, sb:cb384, wu:fa95h05, wu:fa99c12, wu:fb02c06, wu:fd02a10, wu:fj59a10Protein level used designations for COL1A1
- alpha-1 type I collagen
- collagen alpha 1 chain type I
- collagen alpha-1(I) chain
- collagen alpha-1(I) chain preproprotein
- collagen of skin, tendon and bone, alpha-1 chain
- pro-alpha-1 collagen type 1
- alpha-1 type 1 collagen
- procollagen, type I, alpha 1
- collagen, type 1, alpha 1
- procollagen type I, alpha 1
- procollagen, type 1, alpha 1
- collagen, type I, alpha 1
- type I collagen alpha 1 chain
- type I collagen alpha1
- type I collagen pre-pro-alpha1(I) chain
- alpha 1 type I collagen
- collagen, type I, alpha 2
- collagen type I alpha 1
- prepro-alpha-1 collagen type I
- procollagen alpha 1 (I)
- chi
- chihuahua
- med
- microwaved
- collagen 1a1
- pro-alpha-1 type 1 collagen
- alpha-1 collagen (I)
- collagen alpha-1 chain
- collagen, type I, alpha 1b
- collagen, type I, alpha 3
- fj59a10
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