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Coiled-Coil Domain Containing 88C Antibodies

(Coiled-Coil Domain Containing 88C (CCDC88C))
This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus\; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013].

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Featured Coiled-Coil Domain Containing 88C Categories

Coiled-Coil Domain Containing 88C Antibodies

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to Coiled-Coil Domain Containing 88C

coiled-coil domain containing 88C (Ccdc88c), coiled-coil domain containing 88C (CCDC88C), 0610010D24Rik, AV000935, AW324073, Daple, DAPLE, HKRP2, KIAA1509, MGC160122, mKIAA1509, RGD1307429

Protein level used designations for Coiled-Coil Domain Containing 88C

  • DVL-binding protein DAPLE
  • coiled-coil domain-containing protein 88C
  • dvl-associating protein with a high frequency of leucine residues
  • protein Daple
  • coiled-coil domain containing 88C
  • Dvl-associating protein with a high frequency of leucine residues
  • hook-related protein 2
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