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Cofilin 2 Products

(Cofilin 2 (CFL2))
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009].

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Featured Cofilin 2 Categories

Cofilin 2 Antibodies

High quality antibodies with extensive validation data.

Cofilin 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Cofilin 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cofilin 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN560344
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN185454
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN2854655
Quantity 100 μL
Datasheet Datasheet

Recommended Cofilin 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965919
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965920
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2851050
Quantity 96 tests
Datasheet Datasheet

Recommended Cofilin 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122423
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349223
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349221
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Cofilin 2 products

Purde, Busch, Kudryashova, Wysocki, Kudryashov: "Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins." in: International journal of molecular sciences, Vol. 20, Issue 22, (2020) (PubMed).

Bracken, Li, Wright, Lawrence, Pillman, Salmanidis, Anderson, Dredge, Gregory, Tsykin, Neilsen, Thomson, Bert, Leerberg, Yap, Jensen, Khew-Goodall, Goodall: "Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion." in: The EMBO journal, Vol. 33, Issue 18, pp. 2040-56, (2014) (PubMed).

Nakashima, Sato, Nakagaki, Abe, Ono, Obinata: "Two mouse cofilin isoforms, muscle-type (MCF) and non-muscle type (NMCF), interact with F-actin with different efficiencies." in: Journal of biochemistry, Vol. 138, Issue 4, pp. 519-26, (2005) (PubMed).

Thirion, Stucka, Mendel, Gruhler, Jaksch, Nowak, Binz, Laing, Lochmüller: "Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle." in: European journal of biochemistry / FEBS, Vol. 268, Issue 12, pp. 3473-82, (2001) (PubMed).

Synonyms and alternative names related to Cofilin 2

cofilin 2 (CFL2), cofilin 2 (non-muscle) (cfl2), cofilin 2 (Cfl2), cofilin 2 (muscle) (cfl2), cofilin 2 (cf12), cofilin 2, muscle (Cfl2), cofilin-2 (LOC100359205), cf12, CFL2, NEM7, zgc:77288

Protein level used designations for Cofilin 2

  • cofilin, muscle isoform
  • cofilin-2
  • nemaline myopathy type 7
  • cofilin 2 (muscle)
  • cofilin 2
  • LOW QUALITY PROTEIN: cofilin-2
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