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CNTF Products

(Ciliary Neurotrophic Factor (CNTF))

Categories

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010].

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Featured CNTF Categories

CNTF Antibodies

High quality antibodies with extensive validation data.

CNTF ELISA Kits

Reliable ELISA kits for a wide range of species.

CNTF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CNTF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN6260918
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3015705
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3042520
Quantity 100 μg
Datasheet Datasheet

Recommended CNTF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6954807
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954806
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954809
Quantity 96 tests
Datasheet Datasheet

Recommended CNTF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7455693
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122401
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122399
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CNTF products

Labrador-Velandia, Alonso-Alonso, Di Lauro, García-Gutierrez, Srivastava, Pastor, Fernandez-Bueno: "Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures." in: Experimental eye research, Vol. 185, pp. 107671, (2020) (PubMed).

Lian, Chen, Yuan, Chen, Daud M Sayed, Luo, Zhu, Li, Bu: "Cortex Mori Radicis extract attenuates myocardial damages in diabetic rats by regulating ERS." in: Biomedicine & pharmacotherapy, Vol. 90, pp. 777-785, (2018) (PubMed).

Sun, Zhu, Yin, Guo, Xu, Xiao, Jiang, Guo, Meng, Lu, Wang, Peng: "Differentiation of adipose-derived stem cells into Schwann cell-like cells through intermittent induction: potential advantage of cellular transient memory function." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 133, (2018) (PubMed).

Zhao, Zhang, Guo, Cao, Xue, Zhao, Yang, Yang, Ji, Huang, Sun: "Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis." in: Frontiers in molecular neuroscience, Vol. 10, pp. 293, (2017) (PubMed).

Dinis, Elia, Vidal, Dermigny, Denoeud, Kaplan, Egles, Marin: "3D multi-channel bi-functionalized silk electrospun conduits for peripheral nerve regeneration." in: Journal of the mechanical behavior of biomedical materials, Vol. 41, pp. 43-55, (2015) (PubMed).

Yang, Liu, Liu, Xia, He, Liu, Liu, Wang, Liu, Zhou, Zhang, Wang: "Reversal of bone cancer pain by HSV-1-mediated silencing of CNTF in an afferent area of the spinal cord associated with AKT-ERK signal inhibition." in: Current gene therapy, Vol. 14, Issue 5, pp. 377-88, (2015) (PubMed).

Zhou, Chen, Di, Zhang, Wang, Qi, Duan, Xie: "Ciliary neurotrophic factor promotes the activation of corneal epithelial stem/progenitor cells and accelerates corneal epithelial wound healing." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 5, pp. 1566-76, (2015) (PubMed).

Sun, Mandai, Kamao, Hashiguchi, Shikamura, Kawamata, Sugita, Takahashi: "Protective Effects of Human iPS-Derived Retinal Pigmented Epithelial Cells in Comparison with Human Mesenchymal Stromal Cells and Human Neural Stem Cells on the Degenerating Retina in rd1 mice." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 5, pp. 1543-53, (2015) (PubMed).

Fang, Yang, Chiou, Yang: "Induced pluripotent stem cells without c-Myc ameliorate retinal oxidative damage via paracrine effects and reduced oxidative stress in rats." in: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, Vol. 30, Issue 9, pp. 757-70, (2014) (PubMed).

Scuteri, Donzelli, Rodriguez-Menendez, Ravasi, Monfrini, Bonandrini, Figliuzzi, Remuzzi, Tredici: "A double mechanism for the mesenchymal stem cells' positive effect on pancreatic islets." in: PLoS ONE, Vol. 9, Issue 1, pp. e84309, (2014) (PubMed).

Synonyms and alternative names related to CNTF

ciliary neurotrophic factor (CNTF), ciliary neurotrophic factor (Cntf), AI429687, CNTF, GPA, HCNTF

Protein level used designations for CNTF

  • growth-promoting activity factor
  • ciliary neurotrophic factor
  • ciliary neurotropic factor
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