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CLK1 Products

(CDC like Kinase 1 (CLK1))

Categories

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].

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Featured CLK1 Categories

CLK1 Antibodies

High quality antibodies with extensive validation data.

CLK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7186348
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
  • (3)
Cat. No. ABIN2784736
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7150730
Quantity 100 μL
Datasheet Datasheet

Recommended CLK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1130755
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1130756
Quantity 96 tests
Datasheet Datasheet

Recommended CLK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349702
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349700
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508881
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CLK1 products

Aubol, Wu, Keshwani, Movassat, Fattet, Hertel, Fu, Adams: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).

Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

Breig, Baklouti: "Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation." in: PLoS ONE, Vol. 8, Issue 3, pp. e59137, (2013) (PubMed).

Prasad, Manley: "Regulation and substrate specificity of the SR protein kinase Clk/Sty." in: Molecular and cellular biology, Vol. 23, Issue 12, pp. 4139-49, (2003) (PubMed).

Duncan, Howell, Marius, Drmanic, Douville, Bell: "Alternative splicing of STY, a nuclear dual specificity kinase." in: The Journal of biological chemistry, Vol. 270, Issue 37, pp. 21524-31, (1995) (PubMed).

Synonyms and alternative names related to CLK1

CDC like kinase 1 (CLK1), CDC-like kinase 1 (Clk1), CLK, CLK/STY, STY

Protein level used designations for CLK1

  • CDC28/CDC2-like kinase
  • dual specificity protein kinase CLK1
  • protein tyrosine kinase STY
  • protein kinase STY
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