CLK1 Products
(CDC like Kinase 1 (CLK1))
Categories
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
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Featured CLK1 Categories
CLK1 Antibodies
High quality antibodies with extensive validation data.
CLK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7186348
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (2)
- (3)
Cat. No.
ABIN2784736
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7150730
Quantity
100 μL
Datasheet
Datasheet
Recommended CLK1 ELISA Kits
Recommended CLK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349702
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349700
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508881
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CLK1 products
: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).
: "Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation." in: PLoS ONE, Vol. 8, Issue 3, pp. e59137, (2013) (PubMed).
: "Regulation and substrate specificity of the SR protein kinase Clk/Sty." in: Molecular and cellular biology, Vol. 23, Issue 12, pp. 4139-49, (2003) (PubMed).
: "Alternative splicing of STY, a nuclear dual specificity kinase." in: The Journal of biological chemistry, Vol. 270, Issue 37, pp. 21524-31, (1995) (PubMed).
Synonyms and alternative names related to CLK1
CDC like kinase 1 (CLK1), CDC-like kinase 1 (Clk1), CLK, CLK/STY, STYProtein level used designations for CLK1
- CDC28/CDC2-like kinase
- dual specificity protein kinase CLK1
- protein tyrosine kinase STY
- protein kinase STY
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