CLEC7A Products
(C-Type Lectin Domain Family 7, Member A (CLEC7A))
Categories
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].
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Featured CLEC7A Categories
CLEC7A Antibodies
High quality antibodies with extensive validation data.
CLEC7A ELISA Kits
Reliable ELISA kits for a wide range of species.
CLEC7A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLEC7A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA, IHC, ICC, Neut
Validations
- (5)
Cat. No.
ABIN7193336
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7146093
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, IHC (fro)
Validations
- (2)
Cat. No.
ABIN7013961
Quantity
0.1 mg
Datasheet
Datasheet
Recommended CLEC7A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965275
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954230
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954231
Quantity
96 tests
Datasheet
Datasheet
Recommended CLEC7A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274366
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274356
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN5854489
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CLEC7A products
: "Mac-1 triggers neutrophil DNA extracellular trap formation to Aspergillus fumigatus independently of PAD4 histone citrullination." in: Journal of leukocyte biology, Vol. 107, Issue 1, pp. 69-83, (2020) (PubMed).: "Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis." in: Journal of immunology research, Vol. 2019, pp. 1529189, (2019) (PubMed).
: "Xylose rich heteroglycan from flaxseed gum mediates the immunostimulatory effects on macrophages via TLR2 activation." in: Carbohydrate polymers, Vol. 213, pp. 59-69, (2019) (PubMed).
: "Long-term Intake of Pasta Containing Barley (1-3)Beta-D-Glucan Increases Neovascularization-mediated Cardioprotection through Endothelial Upregulation of Vascular Endothelial Growth Factor and Parkin." in: Scientific reports, Vol. 7, Issue 1, pp. 13424, (2019) (PubMed).
: "Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. ..." in: EMBO molecular medicine, Vol. 11, Issue 6, (2019) (PubMed).
: "Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses." in: PLoS biology, Vol. 16, Issue 4, pp. e2005504, (2018) (PubMed).
: "Cellular metabolism constrains innate immune responses in early human ontogeny." in: Nature communications, Vol. 9, Issue 1, pp. 4822, (2018) (PubMed).
: "Kluyveromyces marxianus and Saccharomyces boulardii Induce Distinct Levels of Dendritic Cell Cytokine Secretion and Significantly Different T Cell Responses In Vitro." in: PLoS ONE, Vol. 11, Issue 11, pp. e0167410, (2017) (PubMed).
: "Dectin-1-Mediated Pathway Contributes to Fusarium proliferatum-Induced CXCL-8 Release from Human Respiratory Epithelial Cells." in: International journal of molecular sciences, Vol. 18, Issue 3, (2017) (PubMed).
: "EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans." in: Nature microbiology, Vol. 3, Issue 1, pp. 53-61, (2017) (PubMed).
Synonyms and alternative names related to CLEC7A
C-type lectin domain containing 7A (CLEC7A), C-type lectin domain family 7, member a (Clec7a), C-type lectin domain containing 7A (Clec7a), beta-GR, BGR, CANDF4, CLEC7A, Clec7b, Clecsf12, CLECSF12, DECTIN1, RGD1565140Protein level used designations for CLEC7A
- dendritic cell-associated C-type lectin 1
- C-type lectin domain family 7, member A
- C-type lectin domain family 7 member A
- dectin 1
- C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12
- C-type lectin superfamily member 12
- DC-associated C-type lectin 1
- beta-glucan receptor
- dectin-1
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12
- dendritic cell-associated C-type lectin-1
- lectin-like receptor 1
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