CLEC4E Products
(C-Type Lectin Domain Family 4, Member E (CLEC4E))
Categories
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].
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Featured CLEC4E Categories
CLEC4E Antibodies
High quality antibodies with extensive validation data.
CLEC4E ELISA Kits
Reliable ELISA kits for a wide range of species.
CLEC4E Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLEC4E Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, IHC (p)
Validations
- (9)
Cat. No.
ABIN1497530
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7146077
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
Cat. No.
ABIN565251
Quantity
100 μg
Datasheet
Datasheet
Recommended CLEC4E ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965273
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962135
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN585129
Quantity
96 tests
Datasheet
Datasheet
Recommended CLEC4E Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349662
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2712869
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1096407
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CLEC4E products
: "C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation." in: The Journal of clinical investigation, (2020) (PubMed).: "Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia. ..." in: Cell reports, Vol. 21, Issue 12, pp. 3548-3558, (2018) (PubMed).
: "Mincle signaling in the innate immune response after traumatic brain injury." in: Journal of neurotrauma, Vol. 32, Issue 4, pp. 228-36, (2015) (PubMed).
: "Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats." in: Stroke, Vol. 46, Issue 8, pp. 2277-86, (2015) (PubMed).
: "Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity." in: Cell host & microbe, Vol. 15, Issue 4, pp. 494-505, (2014) (PubMed).
: "Mincle and human B cell function." in: Journal of autoimmunity, Vol. 39, Issue 4, pp. 315-22, (2012) (PubMed).
: "Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans." in: Glycobiology, Vol. 18, Issue 9, pp. 679-85, (2008) (PubMed).
Synonyms and alternative names related to CLEC4E
C-type lectin domain family 4 member E (CLEC4E), C-type lectin domain family 4, member e (Clec4e), C-type lectin domain family 4, member E (Clec4e), C-type lectin domain family 4 member E (LOC611538), C-type lectin domain family 4 member E (Clec4e), C86253, CLEC4E, CLECSF9, Clecsf9, MINCLE, MincleProtein level used designations for CLEC4E
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9
- C-type lectin domain family 4 member E
- C-type lectin superfamily member 9
- macrophage-inducible C-type lectin
- C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9
- C-type lectin, superfamily member 9
- immunoreceptor
- C-type lectin domain family 4, member E
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