CLEC14A Products
(C-Type Lectin Domain Family 14, Member A (CLEC14A))
Categories
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012].
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Featured CLEC14A Categories
CLEC14A Antibodies
High quality antibodies with extensive validation data.
CLEC14A ELISA Kits
Reliable ELISA kits for a wide range of species.
CLEC14A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLEC14A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
- (3)
- (1)
Cat. No.
ABIN1385496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN531111
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7146053
Quantity
100 μg
Datasheet
Datasheet
Recommended CLEC14A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882375
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730716
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386088
Quantity
96 tests
Datasheet
Datasheet
Recommended CLEC14A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274362
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274351
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122062
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CLEC14A products
: "Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a." in: Molecular oncology, Vol. 12, Issue 3, pp. 356-372, (2019) (PubMed).: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." in: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).
: "CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 10666, (2017) (PubMed).
: "Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 6, pp. 2311-23, (2016) (PubMed).
: "Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth." in: Oncogene, (2015) (PubMed).
: "Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro." in: Oncogene, Vol. 32, Issue 48, pp. 5449-57, (2013) (PubMed).
: "Identification and angiogenic role of the novel tumor endothelial marker CLEC14A." in: Oncogene, Vol. 31, Issue 3, pp. 293-305, (2012) (PubMed).
: "Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 64, pp. 112-127 (PubMed).
Synonyms and alternative names related to CLEC14A
C-type lectin domain containing 14A (CLEC14A), C-type lectin domain family 14, member a (Clec14a), 1200003C23Rik, AI642649, C14orf27, CEG1, EGFR-5Protein level used designations for CLEC14A
- C-type lectin domain family 14 member A
- ClECT and EGF-like domain containing protein
- epidermal growth factor receptor 5
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