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CLCNKB Products

(Chloride Channel Kb (CLCNKB))

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The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Featured CLCNKB Categories

CLCNKB Antibodies

High quality antibodies with extensive validation data.

CLCNKB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLCNKB Antibodies

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Reactivity Human
Application WB, ELISA, IHC, IF
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Cat. No. ABIN7147581
Quantity 100 μg
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Reactivity Human
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Cat. No. ABIN6260876
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Reactivity Dog, Human
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Cat. No. ABIN6735463
Quantity 100 μL
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Recommended CLCNKB Proteins

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Reactivity
Source
Validations
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1776902
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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  • (1)
Cat. No. ABIN1349579
Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3113849
Quantity 1 mg
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Latest Publications for our CLCNKB products

Schlingmann, Konrad, Jeck, Waldegger, Reinalter, Holder, Seyberth, Waldegger: "Salt wasting and deafness resulting from mutations in two chloride channels." in: The New England journal of medicine, Vol. 350, Issue 13, pp. 1314-9, (2004) (PubMed).

Maehara, Okamura, Kobayashi, Uchida, Sasaki, Kitamura: "Expression of CLC-KB gene promoter in the mouse cochlea." in: Neuroreport, Vol. 14, Issue 12, pp. 1571-3, (2003) (PubMed).

Jeck, Waldegger, Doroszewicz, Seyberth, Waldegger: "A common sequence variation of the CLCNKB gene strongly activates ClC-Kb chloride channel activity." in: Kidney international, Vol. 65, Issue 1, pp. 190-7, (2003) (PubMed).

Synonyms and alternative names related to CLCNKB

chloride voltage-gated channel Kb (CLCNKB), chloride channel Kb (CLCNKB), chloride channel, voltage-sensitive Kb (Clcnkb), chloride voltage-gated channel Kb (Clcnkb), chloride channel, voltage-sensitive Kb L homeolog (clcnkb.L), chloride channel K (clcnk), chloride channel protein ClC-Ka (LOC100017912), chloride channel protein ClC-Kb (LOC100400180), chloride channel protein ClC-Kb (LOC100590605), chloride channel protein ClC-Kb (LOC100730738), ClC-k, ClC-K2, ClC-K2L, Clc-Ka, ClC-Kb, clc-kb, Clck2, CLCKB, clckb, Clcnk1l, CLCNKA, clcnka-A, CLCNKB, Clcnkb, clk-k2, DKFZp469N0132, x6clck, xCIC-K, xClC-K, zgc:64141

Protein level used designations for CLCNKB

  • chloride channel Kb
  • chloride channel Ka
  • chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka
  • chloride channel protein ClC-Kb
  • clC-K2
  • putative basolateral mTAL chloride channel ClC-Ka
  • chloride channel K2
  • chloride channel, kidney, B
  • CIC-K
  • chloride channel protein ClC-Kb-like
  • chloride channel, voltage-sensitive Kb
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