CLCF1 Products
(Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
Categories
This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].
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Featured CLCF1 Categories
CLCF1 Antibodies
High quality antibodies with extensive validation data.
CLCF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CLCF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLCF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7434866
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7189455
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7439348
Quantity
100 μL
Datasheet
Datasheet
Recommended CLCF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954374
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974988
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954375
Quantity
96 tests
Datasheet
Datasheet
Recommended CLCF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667531
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349561
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN935688
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CLCF1 products
: "Differential secretion of the mutated protein is a major component affecting phenotypic severity in CRLF1-associated disorders." in: European journal of human genetics : EJHG, Vol. 19, Issue 5, pp. 525-33, (2011) (PubMed).Synonyms and alternative names related to CLCF1
cardiotrophin like cytokine factor 1 (clcf1), cardiotrophin like cytokine factor 1 (CLCF1), cardiotrophin-like cytokine factor 1 (Clcf1), cardiotrophin like cytokine factor 1 (Clcf1), cardiotrophin-like cytokine factor 1 (CLCF1), BSF-3, bsf3, BSF3, Bsf3, ciss2, CISS2, clc, CLC, Clc, CLCF1, NNT-1, nnt1, NNT1, nr6, NR6Protein level used designations for CLCF1
- cardiotrophin-like cytokine factor 1
- B-cell stimulating factor 3
- B-cell stimulatory factor 3
- B-cell-stimulating factor 3
- CRLF1 associated cytokine-like factor 1
- neurotrophin-1/B-cell stimulating factor-3
- novel neurotrophin-1
- BSF-3
- NNT-1
- NNT-1/BSF-3
- b cell-stimulating factor 3
- cardiotrophin-like cytokine
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