Claspin Products
(Claspin (CLSPN))
Categories
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured Claspin Categories
Claspin Antibodies
High quality antibodies with extensive validation data.
Recommended Claspin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6260859
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7266402
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN6388311
Quantity
100 μL
Datasheet
Datasheet
Recommended Claspin ELISA Kits
Recommended Claspin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091815
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136084
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Claspin products
: "Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 19, pp. 7344-9, (2012) (PubMed).: "Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix." in: Journal of translational medicine, Vol. 10, pp. 132, (2012) (PubMed).
: "USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation." in: Human molecular genetics, Vol. 20, Issue 11, pp. 2171-81, (2011) (PubMed).
: "ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells." in: Human molecular genetics, Vol. 19, Issue 9, pp. 1690-701, (2010) (PubMed).
: "NK cells recognize and kill human glioblastoma cells with stem cell-like properties." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3530-9, (2009) (PubMed).
: "Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3305-16, (2009) (PubMed).
: "Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia." in: Human molecular genetics, Vol. 17, Issue 5, pp. 679-89, (2008) (PubMed).
: "Chk1 and Claspin potentiate PCNA ubiquitination." in: Genes & development, Vol. 22, Issue 9, pp. 1147-52, (2008) (PubMed).
: "Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7287-98, (2007) (PubMed).
: "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2729-40, (2007) (PubMed).
Synonyms and alternative names related to Claspin
claspin (Clspn), claspin (CLSPN), claspin (clspn), claspin S homeolog (clspn.S), B130025E01, C85083, CLSPN, E130314M08Rik, xClaspinProtein level used designations for Claspin
- claspin homolog (Xenopus laevis)
- claspin
- claspin homolog
- hClaspin
- xClaspin
You are here:
