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CILP Products

(Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins\; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010].

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Featured CILP Categories

CILP Antibodies

High quality antibodies with extensive validation data.

CILP ELISA Kits

Reliable ELISA kits for a wide range of species.

CILP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CILP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7439468
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7440101
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
Cat. No. ABIN2559699
Quantity 100 μL
Datasheet Datasheet

Recommended CILP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN829428
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882357
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5591836
Quantity 96 tests
Datasheet Datasheet

Recommended CILP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349485
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405361
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406344
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CILP products

DeLeon-Pennell, Tian, Zhang, Cates, Iyer, Cannon, Shah, Aiyetan, Halade, Ma, Flynn, Zhang, Jin, Zhang, Lindsey: "CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling." in: Circulation. Cardiovascular genetics, Vol. 9, Issue 1, pp. 14-25, (2016) (PubMed).

Seki, Kawaguchi, Chiba, Mikami, Kizawa, Oya, Mio, Mori, Miyamoto, Masuda, Tsunoda, Kamata, Kubo, Toyama, Kimura, Nakamura, Ikegawa: "A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease." in: Nature genetics, Vol. 37, Issue 6, pp. 607-12, (2005) (PubMed).

Synonyms and alternative names related to CILP

cartilage intermediate layer protein (CILP), cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp), cartilage intermediate layer protein (Cilp), cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (cilp), cartilage intermediate layer protein 1 (LOC100336614), 9830114D16, C130036G17Rik, CILP, CILP-1, HsT18872, im:7137994, NTPPH

Protein level used designations for CILP

  • cartilage intermediate layer protein 1
  • cartilage intermediate layer protein 1 C1
  • cartilage intermediate layer protein 1 C2
  • cartilage intermediate-layer protein
  • CILP-1
  • nucleotide pyrophosphohydrolase
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • cartilage intermediate layer protein 1-like
  • CILP protein
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