CIDEA Products
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
Categories
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010].
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Featured CIDEA Categories
CIDEA Antibodies
High quality antibodies with extensive validation data.
CIDEA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CIDEA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
- (4)
Cat. No.
ABIN514417
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7147273
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN514415
Quantity
100 μL
Datasheet
Datasheet
Recommended CIDEA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6213582
Quantity
96 tests
Datasheet
Datasheet
Recommended CIDEA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349472
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421812
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414642
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CIDEA products
: "Lung cancer-derived extracellular vesicles induced myotube atrophy and adipocyte lipolysis via the extracellular IL-6-mediated STAT3 pathway." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1091-1102, (2019) (PubMed).: "The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis." in: Scientific reports, Vol. 9, Issue 1, pp. 7501, (2019) (PubMed).
: "An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. ..." in: Nature medicine, Vol. 22, Issue 10, pp. 1120-1130, (2016) (PubMed).
: "Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue." in: Nutrition & metabolism, Vol. 13, pp. 91, (2016) (PubMed).
: "Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors." in: Journal of the National Cancer Institute, Vol. 104, Issue 3, pp. 189-210, (2012) (PubMed).
: "Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes." in: Journal of lipid research, Vol. 52, Issue 8, pp. 1450-60, (2011) (PubMed).
: "Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1676-84, (2010) (PubMed).
: "Cidea is associated with lipid droplets and insulin sensitivity in humans." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 22, pp. 7833-8, (2008) (PubMed).
: "ZIP kinase, a novel serine/threonine kinase which mediates apoptosis." in: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1642-51, (1998) (PubMed).
Synonyms and alternative names related to CIDEA
cell death-inducing DFFA-like effector a (CIDEA), cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea), cell death-inducing DFFA-like effector a (Cidea), cell death-inducing DFFA-like effector a (cidea), cell death-inducing DFFA-like effector a L homeolog (cidea.L), AW212747, CIDE-A, cide-a, CIDEA, MGC89985Protein level used designations for CIDEA
- cell death activator CIDE-A
- cell death-inducing DFFA-like effector A
- cell death-inducing DFFA-like effector a
- cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
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