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CHRNA5 Products

(Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010].

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Featured CHRNA5 Categories

CHRNA5 Antibodies

High quality antibodies with extensive validation data.

CHRNA5 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHRNA5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHRNA5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN5611355
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN5611356
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (6)
Cat. No. ABIN5518749
Quantity 100 μg
Datasheet Datasheet

Recommended CHRNA5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954756
Quantity 96 tests
Datasheet Datasheet

Recommended CHRNA5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349404
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6378501
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CHRNA5 products

Ganic, Singh, Luan, Fadista, Johansson, Cyphert, Bennet, Storm, Prost, Ahlenius, Renström, Stein, Groop, Fex, Artner: "MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes." in: Cell reports, Vol. 14, Issue 8, pp. 1991-2002, (2016) (PubMed).

Kim, Choi, Joo, Bae, Ma, Lee, Kim: "Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells." in: PLoS ONE, Vol. 11, Issue 3, pp. e0152591, (2016) (PubMed).

Falvella, Alberio, Noci, Santambrogio, Nosotti, Incarbone, Pastorino, Fasano, Dragani: "Multiple isoforms and differential allelic expression of CHRNA5 in lung tissue and lung adenocarcinoma." in: Carcinogenesis, Vol. 34, Issue 6, pp. 1281-5, (2013) (PubMed).

Kuryatov, Berrettini, Lindstrom: "Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR function." in: Molecular pharmacology, Vol. 79, Issue 1, pp. 119-25, (2010) (PubMed).

Synonyms and alternative names related to CHRNA5

cholinergic receptor, nicotinic, alpha 5 (chrna5), cholinergic receptor nicotinic alpha 5 subunit (CHRNA5), cholinergic receptor nicotinic alpha 5 subunit L homeolog (chrna5.L), cholinergic receptor nicotinic alpha 5 subunit (Chrna5), cholinergic receptor, nicotinic, alpha polypeptide 5 (Chrna5), Acra-5, Acra5, LNCR2, zgc:110642

Protein level used designations for CHRNA5

  • neuronal acetylcholine receptor subunit alpha-5
  • cholinergic receptor, nicotinic, alpha polypeptide 5
  • Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5
  • acetylcholine receptor, nicotinic, alpha 5 (neuronal)
  • neuronal nicotinic acetylcholine receptor, alpha5 subunit
  • acetylcholine receptor alpha 5
  • cholinergic receptor neuronal nicotinic alpha protein 5
  • nicotinic acetylcholine receptor alpha5 subunit
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