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CHRNA2 Products

(Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009].

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Featured CHRNA2 Categories

CHRNA2 Antibodies

High quality antibodies with extensive validation data.

CHRNA2 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHRNA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHRNA2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN5611312
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7161344
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7243172
Quantity 200 μL
Datasheet Datasheet

Recommended CHRNA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN456003
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1144807
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1144808
Quantity 96 tests
Datasheet Datasheet

Recommended CHRNA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349396
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418278
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727181
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our CHRNA2 products

Wang, Kuryatov, Sriram, Jin, Kamenecka, Kenny, Lindstrom: "An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors." in: The Journal of biological chemistry, Vol. 290, Issue 22, pp. 13907-18, (2015) (PubMed).

Synonyms and alternative names related to CHRNA2

cholinergic receptor nicotinic alpha 2 subunit (CHRNA2), cholinergic receptor, nicotinic, alpha 2a (neuronal) (chrna2a), cholinergic receptor nicotinic alpha 2 subunit (Chrna2), cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) (Chrna2), neuronal acetylcholine receptor subunit alpha-2 (CpipJ_CPIJ002436), neuronal acetylcholine receptor subunit alpha-4-like (LOC100370261), neuronal acetylcholine receptor subunit alpha-2 (Tsp_10995), ACHR, Acra-2, Acra2, BC011490, CHRNA2, chrna2, NACHRA2, zgc:136717

Protein level used designations for CHRNA2

  • cholinergic receptor, nicotinic, alpha 2 (neuronal)
  • alpha-2 subunit, nicotinic acetylcholine receptor
  • cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
  • neuronal acetylcholine receptor subunit alpha-2
  • cholinergic receptor, nicotinic, alpha polypeptide 2a
  • nicotinic acetylcholine receptor
  • neuronal acetylcholine receptor subunit alpha-2-like
  • acetylcholine receptor, nicotinic, alpha 2 (neuronal)
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