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Choline Acetyltransferase Products

(Choline O-Acetyltransferase (CHAT))
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].

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Featured Choline Acetyltransferase Categories

Choline Acetyltransferase Antibodies

High quality antibodies with extensive validation data.

Choline Acetyltransferase ELISA Kits

Reliable ELISA kits for a wide range of species.

Choline Acetyltransferase Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Choline Acetyltransferase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN7440704
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN3016135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN3028569
Quantity 0.4 mL
Datasheet Datasheet

Recommended Choline Acetyltransferase ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965795
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965794
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954745
Quantity 96 tests
Datasheet Datasheet

Recommended Choline Acetyltransferase Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122357
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349279
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395305
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Choline Acetyltransferase products

Al Dera, Alassiri, Eleawa, AlKhateeb, Hussein, Dallak, Sakr, Alqahtani, Khalil: "Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca2+-Activated K+ Channels." in: Neurochemical research, Vol. 44, Issue 8, pp. 1851-1868, (2020) (PubMed).

Mellone, Zianni, Stanic, Campanelli, Marino, Ghiglieri, Longhi, Thiolat, Li, Calabresi, Bezard, Picconi, Di Luca, Gardoni: "NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology." in: Neurobiology of disease, Vol. 121, pp. 338-349, (2019) (PubMed).

Bonsi, Ponterio, Vanni, Tassone, Sciamanna, Migliarini, Martella, Meringolo, Dehay, Doudnikoff, Zachariou, Goodchild, Mercuri, DAmelio, Pasqualetti, Bezard, Pisani: "RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models." in: EMBO molecular medicine, Vol. 11, Issue 1, (2019) (PubMed).

Wang, Wu, Wu, Sun, Zhang, Deng, Walker, Qu, Chen, Liu, Han, Dai, Shields, Shields, Sengelaub, Jones, Smith, Xu: "Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery." in: eLife, Vol. 7, (2019) (PubMed).

Burstein, Valsecchi, Kawamata, Bourens, Zeng, Zuberi, Milner, Cloonan, Lutz, Barrientos, Manfredi: "In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions." in: Human molecular genetics, Vol. 27, Issue 1, pp. 160-177, (2018) (PubMed).

Simandi, Pajer, Karolyi, Sieler, Jiang, Kolostyak, Sari, Fekecs, Pap, Patsalos, Contreras, Reho, Papp, Guo, Horvath, Kiss, Keresztessy, Vámosi, Hickman, Xu, Dormann, Hortobagyi, Antal, Nógrádi, Nagy: "Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 35, pp. 7683-7700, (2018) (PubMed).

Palomo, Granatiero, Kawamata, Konrad, Kim, Arreguin, Zhao, Milner, Manfredi: "Parkin is a disease modifier in the mutant SOD1 mouse model of ALS." in: EMBO molecular medicine, Vol. 10, Issue 10, (2018) (PubMed).

Yu, Xia, Tang, Xu, Wei, Chen, Dai, Gong, Bi: "Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation." in: Scientific reports, Vol. 7, pp. 40802, (2018) (PubMed).

Zhao, Xu, Pan, Zhu, Fu, Guo, Lu, Wang: "Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 234, (2018) (PubMed).

Sun, Li, Hu, Huang, Sun, Yang, Wu, Ji, Zhou: "Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract." in: Aging, Vol. 10, Issue 12, pp. 3851-3865, (2018) (PubMed).

Synonyms and alternative names related to Choline Acetyltransferase

choline O-acetyltransferase (CHAT), choline O-acetyltransferase a (chata), choline O-acetyltransferase (Chat), choline acetyltransferase (Chat), carnitine O-acetyltransferase (PGTG_00551), choline acetyltransferase (LOC100533322), B230380D24Rik, CHOACTASE, ChoAcTase, CMS1A, CMS1A2

Protein level used designations for Choline Acetyltransferase

  • acetyl CoA:choline O-acetyltransferase
  • choline acetylase
  • CHOACTase
  • baj
  • choline O-acetyltransferase
  • choline acetyltransferase
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