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Chitotriosidase 1 Products

(Chitotriosidase (CHIT1))

Categories

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012].

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Featured Chitotriosidase 1 Categories

Chitotriosidase 1 Antibodies

High quality antibodies with extensive validation data.

Chitotriosidase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Chitotriosidase 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Chitotriosidase 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7429688
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN969053
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN514388
Quantity 100 μg
Datasheet Datasheet

Recommended Chitotriosidase 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962714
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954712
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954713
Quantity 96 tests
Datasheet Datasheet

Recommended Chitotriosidase 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349332
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349334
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1096386
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Chitotriosidase 1 products

Hendrickx, van Scheppingen, van der Poel, Bossers, Schuurman, van Eden, Hol, Hamann, Huitinga: "Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions." in: Frontiers in immunology, Vol. 8, pp. 1810, (2017) (PubMed).

Berger, Hsieh, Bakele, Marcos, Rieber, Kormann, Mays, Hofer, Neth, Vitkov, Krautgartner, von Schweinitz, Kappler, Hector, Weber, Hartl: "Neutrophils express distinct RNA receptors in a non-canonical way." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19409-17, (2012) (PubMed).

Chien, Lee, Tsai, Chao, Hwu: "Reduction in imiglucerase dosage causes immediate rise of chitotriosidase activity in patients with Gaucher disease." in: Molecular genetics and metabolism, Vol. 101, Issue 1, pp. 90-1, (2010) (PubMed).

Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).

Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).

Synonyms and alternative names related to Chitotriosidase 1

chitinase 1 (CHIT1), chitinase 1 (chitotriosidase) (chit1), chitinase 1 (Chit1), chitinase 1 (chitotriosidase) (Chit1), 2300002L19Rik, CHI3, chio, CHIT, CHIT1, CHITD

Protein level used designations for Chitotriosidase 1

  • chitotriosidase-1
  • plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
  • chitinase 1 (chitotriosidase)
  • chitotriosidase
  • chitinase-1
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