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CHI3L1 Products

(Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Categories

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009].

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Featured CHI3L1 Categories

CHI3L1 Antibodies

High quality antibodies with extensive validation data.

CHI3L1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHI3L1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHI3L1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7433657
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN3022445
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN737556
Quantity 100 μL
Datasheet Datasheet

Recommended CHI3L1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6954708
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965769
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965767
Quantity 96 tests
Datasheet Datasheet

Recommended CHI3L1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275852
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source CHO Cells
Validations
  • (1)
Cat. No. ABIN2128523
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CHI3L1 products

Deutschmann, Sowa, Murugaiyan, Roesler, Röber, Conrad, Laass, Bogdanos, Sipeki, Papp, Rödiger, Roggenbuck, Schierack: "Identification of Chitinase-3-Like Protein 1 as a Novel Neutrophil Antigenic Target in Crohn's Disease." in: Journal of Crohn's & colitis, Vol. 13, Issue 7, pp. 894-904, (2020) (PubMed).

Jiang, Xu, Zhang, Tang, Peng: "Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of Chi3l1 expression." in: European review for medical and pharmacological sciences, Vol. 23, Issue 7, pp. 3012-3020, (2020) (PubMed).

Wang, Lv, Luo, Mou, Liu, Liu, Deng, Jiang, Lin, Wu, Liu, He, Jiang: "Plasma YKL-40 and NGAL are useful in distinguishing ACO from asthma and COPD." in: Respiratory research, Vol. 19, Issue 1, pp. 47, (2018) (PubMed).

Vela, Leshoski, Vela, Jakupaj, Mladenov, Sopi: "Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine." in: BMC endocrine disorders, Vol. 17, Issue 1, pp. 53, (2018) (PubMed).

Shan, Liu, Chen, Wang, Gao, Xu, Dar, Lee, Elias, Castillo, Di Paola, Ju: "Chitinase 3-like-1 promotes intrahepatic activation of coagulation through induction of tissue factor in mice." in: Hepatology (Baltimore, Md.), Vol. 67, Issue 6, pp. 2384-2396, (2018) (PubMed).

Gerin, Sener, Erman, Yilmaz, Aydin, Armutcu, Gurel: "The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis." in: Inflammation, Vol. 39, Issue 2, pp. 700-5, (2017) (PubMed).

Dündar, Aşık, Ulaşlı, Sınıcı, Yaman, Solak, Toktaş, Eroğlu: "Assessment of pulsed electromagnetic field therapy with Serum YKL-40 and ultrasonography in patients with knee osteoarthritis." in: International journal of rheumatic diseases, Vol. 19, Issue 3, pp. 287-93, (2016) (PubMed).

Lai, Wu, Chen, Cao, Jing, Huang, Lv, Zhao, Lv, Wang, Li, Wu, Shen: "YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodeling." in: Respiratory research, Vol. 17, pp. 31, (2016) (PubMed).

Erfan, Guzel, Alpsoy, Rifaioglu, Kaya, Kucukyalc?n, Topcu, Kulac: "Serum YKL-40: a potential biomarker for psoriasis or endothelial dysfunction in psoriasis?" in: Molecular and cellular biochemistry, Vol. 400, Issue 1-2, pp. 207-12, (2015) (PubMed).

Lai, Chen, Deng, L, Wu, Li, Wu: "YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatment." in: BMC pulmonary medicine, Vol. 15, pp. 1, (2015) (PubMed).

Synonyms and alternative names related to CHI3L1

chitinase-like 1 (Chil1), chitinase 3 like 1 (CHI3L1), chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1), chitinase 3 like 1 (Chi3l1), ASRT7, AW208766, BP40, Brp39, CGP-39, Chil1, CLP-1, GP-39, GP38K, Gp39, GP39, HC-gp39, HCGP-3P, hCGP-39, MGP-40, SPC-40, SPS-40, YKL-40, YKL40, YYL-40

Protein level used designations for CHI3L1

  • CGP-39
  • GP-39
  • cartilage glycoprotein 39
  • chitinase-3-like protein 1
  • 39 kDa synovial protein
  • 38 kDa heparin-binding glycoprotein
  • signal-processing protein
  • 39 kDa whey protein
  • 40 kDa secretory signalling glycoprotein
  • cartilage glycoprotein-39
  • chitinase-like protein 1
  • signal processing protein
  • chitinase 3-like 1 protein
  • mammary gland protein 40
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