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Chemokine (C-X-C Motif) Receptor 4 Products

(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

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This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured Chemokine (C-X-C Motif) Receptor 4 Categories

Chemokine (C-X-C Motif) Receptor 4 Antibodies

High quality antibodies with extensive validation data.

Chemokine (C-X-C Motif) Receptor 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Chemokine (C-X-C Motif) Receptor 4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Chemokine (C-X-C Motif) Receptor 4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (16)
  • (8)
Cat. No. ABIN730888
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
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  • (6)
Cat. No. ABIN521674
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7432925
Quantity 100 μL
Datasheet Datasheet

Recommended Chemokine (C-X-C Motif) Receptor 4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
Cat. No. ABIN6954697
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6973419
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
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Cat. No. ABIN6954699
Quantity 96 tests
Datasheet Datasheet

Recommended Chemokine (C-X-C Motif) Receptor 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491625
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122343
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964154
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Chemokine (C-X-C Motif) Receptor 4 products

Eweida, Flechtenmacher, Sandberg, Schulte, Schmidt, Kneser, Harhaus: "Systemically injected bone marrow mononuclear cells specifically home to axially vascularized tissue engineering constructs." in: PloS one, Vol. 17, Issue 8, pp. e0272697, (2022) (PubMed).

Li, Fong, Gritsina, Zhang, Zhao, Kim, Sharp, Yuan, Aversa, Yang, Nelson, Feng, Chinnaiyan, de Bono, Morrissey, Rettig, Yu: "Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2580-2592, (2019) (PubMed).

Heo, Zhao, Sultan, Zhang, Detering, Luehmann, Zhang, Li, Choksi, Sharp, Levingston, Primeau, Reichert, Sun, Razani, Li, Weilbaecher, Dehdashti, Wooley, Liu: "Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation." in: ACS applied materials & interfaces, Vol. 11, Issue 22, pp. 19669-19678, (2019) (PubMed).

Yang, Wei, Cui, Park, Shah, Deng, Aplin, Lu, Hwang, He, He: "m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade." in: Nature communications, Vol. 10, Issue 1, pp. 2782, (2019) (PubMed).

Ma, Zhang, Liu, Liu, Du, Li, Chen, Bao, Suh, Avery, Deng, Zhou, Wu, Sheth, Wang, Zhou: "Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 15, Issue 35, pp. e1902011, (2019) (PubMed).

Sha, Yang, Lv: "MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis." in: Journal of cellular physiology, Vol. 234, Issue 6, pp. 8846-8861, (2019) (PubMed).

Ieranò, DAlterio, Giarra, Napolitano, Rea, Portella, Santagata, Trotta, Barbieri, Campani, Luciano, Arra, Anniciello, Botti, Mayol, De Rosa, Pacelli, Scala: "CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells." in: Cell death & disease, Vol. 10, Issue 8, pp. 562, (2019) (PubMed).

Wu, Grotefend, Tsai, Wang, Radic, Eoh, Huang: "Δ20 IFITM2 differentially restricts X4 and R5 HIV-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 27, pp. 7112-7117, (2018) (PubMed).

Dinkel, Kremer, Rollins, Medlyn, Hedin: "GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion." in: The Journal of biological chemistry, Vol. 293, Issue 36, pp. 14022-14039, (2018) (PubMed).

Pelagalli, Nardelli, Lucarelli, Zannetti, Brunetti: "Autocrine signals increase ovine mesenchymal stem cells migration through Aquaporin-1 and CXCR4 overexpression." in: Journal of cellular physiology, Vol. 233, Issue 8, pp. 6241-6249, (2018) (PubMed).

Synonyms and alternative names related to Chemokine (C-X-C Motif) Receptor 4

C-X-C motif chemokine receptor 4 (CXCR4), chemokine (C-X-C motif) receptor 4 (Cxcr4), C-X-C motif chemokine receptor 4 (Cxcr4), C-X-C motif chemokine receptor 4 S homeolog (cxcr4.S), C-X-C motif chemokine receptor 4 (cxcr4), C-X-C chemokine receptor type 4 (LOC100049444), C-X-C motif chemokine receptor 4 L homeolog (cxcr4.L), chemokine (C-X-C motif), receptor 4b (cxcr4b), chemokine (C-X-C motif) receptor 4a (cxcr4a), cb403, cb824, CD184, cd184, Cmkar4, CXC-R4, CXC-R4-A, CXC-R4-B, CXCR-4, CXCR-4-A, CXCR-4-B, cxcr4, CXCR4, D2S201E, d2s201e, FB22, fb22, HM89, hm89, HSY3RR, hsy3rr, LAP3, lap3, LCR1, lcr1, LESTR, lestr, NPY3R, npy3r, NPYR, npyr, NPYRL, npyrl, NPYY3R, npyy3r, PB-CKR, PBSF/SDF-1, Sdf1r, WHIM, whim, xcxcr4, xCXCR4, zgc:109863

Protein level used designations for Chemokine (C-X-C Motif) Receptor 4

  • C-X-C chemokine receptor type 4
  • CD184 antigen
  • CXC-R4
  • CXCR-4
  • SDF-1 receptor
  • fusin
  • leukocyte-derived seven transmembrane domain receptor
  • leukocyte-derived seven-transmembrane-domain receptor
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • seven transmembrane helix receptor
  • seven-transmembrane-segment receptor, spleen
  • stromal cell-derived factor 1 receptor
  • CXC chemokine receptor 4
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C) receptor 4
  • chemokine receptor 4
  • leukocyte-expressed seven-transmembrane-domain
  • pre-B-cell-derived chemokine receptor
  • CXC chemokine receptor
  • LESTR
  • chemokine receptor (LCR1)
  • LCR1
  • C-X-C chemokine receptor type 4-B
  • SDF-1 receptor B
  • SDF-1 receptor-B
  • Stromal cell-derived factor 1 receptor-B
  • stromal cell-derived factor 1 receptor B
  • chemokine receptor CXCR4
  • Stromal cell-derived factor 1 receptor
  • C-X-C chemokine receptor type 4-A
  • SDF-1 receptor A
  • SDF-1 receptor-A
  • Stromal cell-derived factor 1 receptor-A
  • stromal cell-derived factor 1 receptor A
  • ody
  • odysseus
  • chemokine (C-X-C motif) receptor 4a
  • LOW QUALITY PROTEIN: C-X-C chemokine receptor type 4
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