CHD8 Products
(Chromodomain Helicase DNA Binding Protein 8 (CHD8))
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This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Featured CHD8 Categories
CHD8 Antibodies
High quality antibodies with extensive validation data.
Recommended CHD8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN6260798
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN566153
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN1774862
Quantity
200 μL
Datasheet
Datasheet
Recommended CHD8 Proteins
Latest Publications for our CHD8 products
: "Common CHD8 Genomic Targets Contrast With Model-Specific Transcriptional Impacts of CHD8 Haploinsufficiency." in: Frontiers in molecular neuroscience, Vol. 11, pp. 481, (2018) (PubMed).: "Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits." in: Cell reports, Vol. 19, Issue 2, pp. 335-350, (2017) (PubMed).
: "BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors." in: Journal of proteomics, Vol. 118, pp. 95-111, (2015) (PubMed).
: "CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 42, pp. E4468-77, (2014) (PubMed).
: "Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 12, pp. 1018-27, (2014) (PubMed).
: "Regulation of serum response factor activity and smooth muscle cell apoptosis by chromodomain helicase DNA-binding protein 8." in: American journal of physiology. Cell physiology, Vol. 299, Issue 5, pp. C1058-67, (2010) (PubMed).
Synonyms and alternative names related to CHD8
chromodomain helicase DNA binding protein 8 (CHD8), chromodomain helicase DNA binding protein 8 (chd8), chromodomain helicase DNA binding protein 8 (Chd8), 5830451P18Rik, AU015341, AUTS18, CHD-8, CHD8, Chd8, Duplin, fi45h08, HELSNF1, mKIAA1564, si:ch211-10e2.6, wu:fi45h08Protein level used designations for CHD8
- chromodomain helicase DNA binding protein 8
- chromodomain-helicase-DNA-binding protein 8
- ATP-dependent helicase CHD8
- chromodomain-helicase-DNA-binding protein 8-like
- axis duplication inhibitor
- duplin
- helicase with SNF2 domain 1
- CHD-8
- beta-catenin binding protein
- chromodomain helicase DNA binding protein family
Did you look for something else?
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- Checkpoint with Forkhead and Ring Finger Domains
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- Chemokine (C-C Motif) Ligand 4-Like 2
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- Chemokine (C-X-C Motif) Receptor 3
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- Chemokine-Binding Protein
- CHERP
- CHGB
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