CFP Products
(Complement Factor P (CFP))
Categories
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009].
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Featured CFP Categories
CFP Antibodies
High quality antibodies with extensive validation data.
CFP ELISA Kits
Reliable ELISA kits for a wide range of species.
CFP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CFP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6138467
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7432592
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (p), IHC (p)
Validations
- (1)
- (1)
Cat. No.
ABIN1386799
Quantity
100 μL
Datasheet
Datasheet
Recommended CFP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6574207
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966040
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966039
Quantity
96 tests
Datasheet
Datasheet
Recommended CFP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1782459
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349230
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2128510
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CFP products
: "Complement alternative pathway activation associated with pulmonary hypertension in lupus nephritis patients." in: Lupus, Vol. 28, Issue 9, pp. 1051-1061, (2020) (PubMed).: "The alternative complement pathway in ANCA-associated vasculitis: further evidence and a meta-analysis." in: Clinical and experimental immunology, Vol. 202, Issue 3, pp. 394-402, (2020) (PubMed).
: "Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids." in: PLoS ONE, Vol. 11, Issue 8, pp. e0159828, (2017) (PubMed).
: "Pharmacological disruption of hepatitis C NS5A protein intra- and intermolecular conformations." in: The Journal of general virology, Vol. 95, Issue Pt 2, pp. 363-72, (2014) (PubMed).
: "Complement in patients receiving maintenance hemodialysis: functional screening and quantitative analysis." in: BMC nephrology, Vol. 11, pp. 34, (2010) (PubMed).
: "The role of properdin in the assembly of the alternative pathway C3 convertases of complement." in: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2128-32, (2006) (PubMed).
Synonyms and alternative names related to CFP
complement factor properdin (CFP), complement factor properdin (Cfp), BCFG, BFD, PFC, Pfc, PFD, PROPERDIN, ProperdinProtein level used designations for CFP
- complement factor P
- properdin
- properdin P factor, complement
- properdin factor, complement
- Properdin P factor, complement
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