CFHR5 Products
(Complement Factor H-Related 5 (CFHR5))
Categories
This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010].
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Featured CFHR5 Categories
CFHR5 Antibodies
High quality antibodies with extensive validation data.
CFHR5 ELISA Kits
Reliable ELISA kits for a wide range of species.
CFHR5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CFHR5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC
Validations
- (8)
Cat. No.
ABIN5542640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, IHC, ICC
Validations
- (7)
Cat. No.
ABIN5542639
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN651876
Quantity
400 μL
Datasheet
Datasheet
Recommended CFHR5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955035
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2702908
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386029
Quantity
96 tests
Datasheet
Datasheet
Recommended CFHR5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349213
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1880676
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318330
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CFHR5 products
: "Rapid isolation of pure Complement Factor H from serum for functional studies by the use of a monoclonal antibody that discriminates FH from all the other isoforms." in: Molecular immunology, Vol. 72, pp. 65-73, (2016) (PubMed).: "A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry." in: Kidney international, Vol. 85, Issue 4, pp. 933-7, (2014) (PubMed).
Synonyms and alternative names related to CFHR5
complement factor H related 5 (CFHR5), CFHL5, CFHR5D, FHR-5, FHR5Protein level used designations for CFHR5
- complement factor H-related protein 5
- factor H-related protein 5
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