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CERS6 Products

(Ceramide Synthase 6 (CERS6))
May be involved in sphingolipid synthesis or its regulation (By similarity).

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Featured CERS6 Categories

CERS6 Antibodies

High quality antibodies with extensive validation data.

CERS6 ELISA Kits

Reliable ELISA kits for a wide range of species.

CERS6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CERS6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (7)
  • (4)
Cat. No. ABIN566979
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (4)
Cat. No. ABIN531439
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (9)
  • (2)
Cat. No. ABIN566978
Quantity 50 μL
Datasheet Datasheet

Recommended CERS6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954559
Quantity 96 tests
Datasheet Datasheet

Recommended CERS6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309181
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309183
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3101953
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CERS6 products

Fekry, Jeffries, Esmaeilniakooshkghazi, Szulc, Knagge, Kirchner, Horita, Krupenko, Krupenko: "C16-ceramide is a natural regulatory ligand of p53 in cellular stress response." in: Nature communications, Vol. 9, Issue 1, pp. 4149, (2019) (PubMed).

Suzuki, Cao, Kato, Komizu, Mizutani, Tanaka, Arima, Tai, Yanagisawa, Togawa, Shiraishi, Usami, Taniguchi, Fukui, Yokoi, Wakahara, Hasegawa, Mizutani, Igarashi, Inokuchi, Iwaki, Fujii, Satou et al.: "Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).

Gerl, Bittl, Kirchner, Sachsenheimer, Brunner, Lüchtenborg, Özbalci, Wiedemann, Wegehingel, Nickel, Haberkant, Schultz, Krüger, Brügger: "Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153009, (2016) (PubMed).

Schüll, Günther, Brodesser, Seeger, Tosetti, Wiegmann, Pongratz, Diaz, Witt, Andree, Brinkmann, Krönke, Wiesner, Kashkar: "Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6." in: Cell death & disease, Vol. 6, pp. e1691, (2015) (PubMed).

Jensen, Calvert, Volpert, Kouri, Hurley, Luciano, Wu, Chalastanis, Futerman, Stegh: "Bcl2L13 is a ceramide synthase inhibitor in glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 15, pp. 5682-7, (2014) (PubMed).

Cheng, Bai, Beckham, Marrison, Yount, Young, Lu, Bartlett, Wu, Keane, Armeson, Marshall, Keane, Smith, Jones, Drake, Bielawska, Norris, Liu: "Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse." in: The Journal of clinical investigation, Vol. 123, Issue 10, pp. 4344-58, (2013) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).

Laviad, Kelly, Merrill, Futerman: "Modulation of ceramide synthase activity via dimerization." in: The Journal of biological chemistry, Vol. 287, Issue 25, pp. 21025-33, (2012) (PubMed).

Senkal, Ponnusamy, Manevich, Meyers-Needham, Saddoughi, Mukhopadyay, Dent, Bielawski, Ogretmen et al.: "Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi ..." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 42446-58, (2011) (PubMed).

Synonyms and alternative names related to CERS6

ceramide synthase 6 (CERS6), ceramide synthase 6 (cers6), ceramide synthase 6 (Cers6), 4732462C07Rik, AW544719, CERS5, CERS6, LASS6, Lass6, RGD1561599, si:ch211-278b7.1, T1L

Protein level used designations for CERS6

  • LAG1 homolog, ceramide synthase 6
  • lass6
  • longevity assurance homolog 6
  • LAG1 longevity assurance homolog 6
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