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CENPW Products

(Centromere Protein W (CENPW))
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis (By similarity).

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Featured CENPW Categories

CENPW Antibodies

High quality antibodies with extensive validation data.

CENPW ELISA Kits

Reliable ELISA kits for a wide range of species.

CENPW Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CENPW Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IHC
Validations
  • (2)
Cat. No. ABIN1804197
Quantity 0.05 mg
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC
Validations
Cat. No. ABIN2171735
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN2171740
Quantity 100 μL
Datasheet Datasheet

Recommended CENPW ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742828
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773732
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745268
Quantity 96 tests
Datasheet Datasheet

Recommended CENPW Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752755
Quantity 25 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1476268
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CENPW products

Chun, Kim, Lee: "Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149127, (2016) (PubMed).

Synonyms and alternative names related to CENPW

centromere protein W (CENPW), centromere protein W (Cenpw), 2610036L11Rik, C6orf173, CENP-W, CUG2, Cug2

Protein level used designations for CENPW

  • centromere protein W
  • CENP-W
  • cancer-up-regulated gene 2 protein
  • cancer-upregulated gene 2
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