CENPF Products
(Centromere Protein F (CENPF))
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This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008].
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Featured CENPF Categories
CENPF Antibodies
High quality antibodies with extensive validation data.
CENPF ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended CENPF Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC, IHC (wm)
Validations
- (1)
- (3)
Cat. No.
ABIN2854654
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p), ICC, IHC (fro)
Validations
- (2)
Cat. No.
ABIN7431644
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN6260754
Quantity
100 μL
Datasheet
Datasheet
Recommended CENPF ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965627
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954556
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742813
Quantity
96 tests
Datasheet
Datasheet
Recommended CENPF Proteins
Latest Publications for our CENPF products
: "Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1." in: Scientific reports, Vol. 7, pp. 41812, (2018) (PubMed).: "Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer." in: Journal of ovarian research, Vol. 11, Issue 1, pp. 27, (2018) (PubMed).
: "The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases." in: The Journal of biological chemistry, Vol. 293, Issue 26, pp. 10084-10101, (2018) (PubMed).
: "Microtubules assemble near most kinetochores during early prometaphase in human cells." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2647-2659, (2018) (PubMed).
: "Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion." in: Current biology : CB, Vol. 28, Issue 21, pp. 3422-3429.e5, (2018) (PubMed).
: "Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells." in: The Journal of cell biology, Vol. 212, Issue 3, pp. 307-19, (2016) (PubMed).
: "Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4026-35, (2015) (PubMed).
: "CaMKKβ-AMPKα2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 4, pp. 598-611, (2015) (PubMed).
: "Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122582, (2015) (PubMed).
: "A nonsense mutation of human XRCC4 is associated with adult-onset progressive encephalocardiomyopathy." in: EMBO molecular medicine, Vol. 7, Issue 7, pp. 918-29, (2015) (PubMed).
Synonyms and alternative names related to CENPF
centromere protein F (CENPF), centromere protein F (Cenpf), centromere protein F (cenpf), 6530404A22Rik, AI325968, CENF, CMF1, hcp-1, im:7140452, im:7144238, im:7154719, im:7156761, Lek1, LOC100222985, mitosin, PRO1779, si:ch211-152h14.2Protein level used designations for CENPF
- centromere protein F
- centromere autoantigen F
- leucine, glutamic acid, lysine family 1 protein
- LEK/centromere protein
- AH antigen
- CENP-F kinetochore protein
- cell-cycle-dependent 350K nuclear protein
- centromere protein F, 350/400kDa (mitosin)
- centromere protein F, 350/400ka (mitosin)
- kinetochore protein CENPF
- mitosin
- cardiac muscle factor 1 CMF1
Did you look for something else?
- CENPE
- CENPC1
- CENPBD1
- CENPB
- CENPA
- CENP-C1
- CEND1
- CEMP1
- CEMIP
- CELSR3
- CELSR2
- CELSR1
- Cellulase
- Cellular Retinoic Acid Binding Protein 2
- Cellular Retinoic Acid Binding Protein 1
- Cellular Fibronectin
- Cell Division Cycle Associated 9
- Cell Division Cycle 34
- Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1)
- Cell Adhesion Molecule 4
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