CENPB Products
(Centromere Protein B (CENPB))
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This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008].
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Featured CENPB Categories
CENPB Antibodies
High quality antibodies with extensive validation data.
CENPB ELISA Kits
Reliable ELISA kits for a wide range of species.
CENPB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CENPB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN514341
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN514342
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC, IP
Validations
- (2)
Cat. No.
ABIN6971525
Quantity
100 μL
Datasheet
Datasheet
Recommended CENPB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965626
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1114052
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5564601
Quantity
96 tests
Datasheet
Datasheet
Recommended CENPB Proteins
Latest Publications for our CENPB products
: "A two-step mechanism for epigenetic specification of centromere identity and function." in: Nature cell biology, Vol. 15, Issue 9, pp. 1056-66, (2013) (PubMed).Synonyms and alternative names related to CENPB
centromere protein B (CENPB), centromere protein B (Cenpb), centromere protein B, 80kDa (Cenpb), CENP-B, CENPBProtein level used designations for CENPB
- CENP-B
- centromere autoantigen B
- major centromere autoantigen B
- CENP-B protein
- centromere protein B
- Major centromere autoantigen B
- centromere autoantigen protein B
- centromere protein B, 80kDa
- LOW QUALITY PROTEIN: major centromere autoantigen B
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