CDT1 Products
(Chromatin Licensing and DNA Replication Factor 1 (CDT1))
Categories
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011].
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Featured CDT1 Categories
CDT1 Antibodies
High quality antibodies with extensive validation data.
CDT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CDT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (3)
Cat. No.
ABIN7244654
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN184819
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat, Saccharomyces cerevisiae
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN2782592
Quantity
100 μL
Datasheet
Datasheet
Recommended CDT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965806
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1130184
Quantity
96 tests
Datasheet
Datasheet
Recommended CDT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091136
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3126788
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2713887
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our CDT1 products
: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases." in: Nature cell biology, Vol. 12, Issue 4, pp. 351-61, (2010) (PubMed).
: "Histamine suppresses fibulin-5 and insulin-like growth factor-II receptor expression in melanoma." in: Cancer research, Vol. 68, Issue 6, pp. 1997-2005, (2008) (PubMed).
: "The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing." in: Genes & development, Vol. 22, Issue 18, pp. 2507-19, (2008) (PubMed).
: "Oncogenic potential of the DNA replication licensing protein CDT1." in: Oncogene, Vol. 21, Issue 8, pp. 1150-8, (2002) (PubMed).
: "Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase ..." in: Genes & development, Vol. 14, Issue 14, pp. 1765-76, (2000) (PubMed).
Synonyms and alternative names related to CDT1
chromatin licensing and DNA replication factor 1 (CDT1), chromatin licensing and DNA replication factor 1 (cdt1), chromatin licensing and DNA replication factor 1 (Cdt1), chromatin licensing and DNA replication factor 1 L homeolog (cdt1.L), 2610318F11Rik, AW545653, C76791, CDT1, DUP, dup, fc37h07, im:7158083, RIS2, Ris2, ris2, wu:fc37h07, wu:fi38h09, xcdt1Protein level used designations for CDT1
- chromatin licensing and DNA replication factor 1
- DNA replication factor Cdt1-like
- DNA replication factor Cdt1
- Double parked, Drosophila, homolog of
- DUP
- double parked homolog
- retroviral insertion site 2 protein
- retroviral integration site 1
- retroviral integration site 2
- DNA replication factor
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