CDKN1C Products
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
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Featured CDKN1C Categories
CDKN1C Antibodies
High quality antibodies with extensive validation data.
CDKN1C ELISA Kits
Reliable ELISA kits for a wide range of species.
CDKN1C Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDKN1C Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC
Validations
- (6)
Cat. No.
ABIN7193625
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC
Validations
- (8)
Cat. No.
ABIN7193626
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (f)
Validations
- (3)
Cat. No.
ABIN7504181
Quantity
100 μg
Datasheet
Datasheet
Recommended CDKN1C ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380426
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended CDKN1C Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122539
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349015
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091606
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CDKN1C products
: "Long non-coding RNA NEAT1 regulates E2F3 expression by competitively binding to miR-377 in non-small cell lung cancer." in: Oncology letters, Vol. 14, Issue 4, pp. 4983-4988, (2018) (PubMed).: "CD271 regulates the proliferation and motility of hypopharyngeal cancer cells." in: Scientific reports, Vol. 6, pp. 30707, (2016) (PubMed).
: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).
: "Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)." in: Oncogene, Vol. 11, Issue 2, pp. 211-9, (1995) (PubMed).
: "Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution." in: Genes & development, Vol. 9, Issue 6, pp. 639-49, (1995) (PubMed).
: "p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene." in: Genes & development, Vol. 9, Issue 6, pp. 650-62, (1995) (PubMed).
Synonyms and alternative names related to CDKN1C
cyclin dependent kinase inhibitor 1C (CDKN1C), cyclin-dependent kinase inhibitor 1Ca (cdkn1ca), cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), cyclin-dependent kinase inhibitor 1C (Cdkn1c), AL024410, BWCR, BWS, cb961, CDKI, KIP2, Kip2, p27Xic1-a, p57, p57(kip2), p57Kip2, p57KIP2, WBS, zgc:86618Protein level used designations for CDKN1C
- cyclin-dependent kinase inhibitor 1C
- cyclin-dependent kinase inhibitor p57
- cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- p57kip2
- cyclin-dependent kinase inhibitor 1C, p57
- p57KIP2 A3sh
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