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CDKN1B Products

(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Categories

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry (By similarity).

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Featured CDKN1B Categories

CDKN1B Antibodies

High quality antibodies with extensive validation data.

CDKN1B ELISA Kits

Reliable ELISA kits for a wide range of species.

CDKN1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDKN1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (5)
  • (7)
Cat. No. ABIN672621
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), PLA
Validations
  • (1)
  • (8)
Cat. No. ABIN4888951
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), IP, ICC, IHC (fro)
Validations
  • (3)
  • (8)
Cat. No. ABIN2854753
Quantity 100 μL
Datasheet Datasheet

Recommended CDKN1B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966178
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966177
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955165
Quantity 96 tests
Datasheet Datasheet

Recommended CDKN1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122537
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349013
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349011
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CDKN1B products

Yu, Zheng, Li, Lin, Chen, Tian, Chen, Zhang, Xu, Shen: "The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 327, (2021) (PubMed).

Abdalla, Li, Nie: "A Novel DNA Methyltransferase Dnmt3a3 Splice Variant Represses Preadipocyte Proliferation and Differentiation." in: Frontiers in genetics, Vol. 11, pp. 115, (2020) (PubMed).

Mishra, Stephenson, Chalfant, Brown: "Upregulation of human glycolipid transfer protein (GLTP) induces necroptosis in colon carcinoma cells." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 2, pp. 158-167, (2019) (PubMed).

Zhang, Miao, Li, Cui, Ge, Chen: "S-phase kinase-associated protein 2 impairs the inhibitory effects of miR-1236-3p on bladder tumors." in: American journal of translational research, Vol. 10, Issue 3, pp. 731-743, (2018) (PubMed).

Lin, Li, Ye, Chen, Zhang, Wang, Xi, Bu, Qiu: "LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells." in: Gene, (2018) (PubMed).

Chen, Xu, Yang, Zhang, Wu, Chen, Li, Wang, Li, Li, Dai: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).

Li, Kang, Yin, Li, Chen, Li, Zhang, Qiu: "Ginsenoside Rh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 3062-3068, (2018) (PubMed).

Scully, Lahmy, Signaevskaia, Sasik, Medal, Kim, French, James, Wu, Lowy, Itkin-Ansari: "E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53." in: Cellular and molecular gastroenterology and hepatology, Vol. 6, Issue 2, pp. 181-198, (2018) (PubMed).

Mlcochova, Caswell, Taylor, Towers, Gupta: "DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages." in: The EMBO journal, Vol. 37, Issue 1, pp. 50-62, (2018) (PubMed).

Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).

Synonyms and alternative names related to CDKN1B

cyclin dependent kinase inhibitor 1B (CDKN1B), cyclin-dependent kinase inhibitor 1Bb (cdkn1bb), interferon alpha inducible protein 27 (IFI27), cyclin-dependent kinase inhibitor 1B (Cdkn1b), cyclin dependent kinase inhibitor 1B (Cdkn1b), cyclin-dependent kinase inhibitor 1Ba (cdkn1ba), AA408329, AI843786, Cdki1b, cdkn1b, CDKN1B, cdkn1bl, CDKN4, FAM14D, ISG12, ISG12A, KIP1, Kip1, MEN1B, MEN4, p27, P27, P27KIP1, p27Kip1, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03

Protein level used designations for CDKN1B

  • cyclin-dependent kinase inhibitor 1B
  • cyclin-dependent kinase inhibitor 1b (p27, kip1)
  • fb64g10
  • kip1
  • p27
  • cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cyclin-dependent kinase inhibitor p27
  • p27Kip1
  • 2310061N23Rik
  • ISG12(a)
  • interferon alpha-induced 11.5 kDa protein
  • interferon alpha-inducible protein 27, mitochondrial
  • interferon-stimulated gene 12a protein
  • Cyclin-dependent kinase inhibitor 1B (p27 Kip1)
  • Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cyclin-dependent kinase inhibitor p27/Kip1
  • Cyclin-dependent kinase inhibitor p27
  • cyclin-dependent kinase inhibitor 1b, like
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