CDKL5 Products
(Cyclin-Dependent Kinase-Like 5 (CDKL5))
Categories
This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].
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Featured CDKL5 Categories
CDKL5 Antibodies
High quality antibodies with extensive validation data.
CDKL5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDKL5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6260727
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN391362
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN563054
Quantity
100 μg
Datasheet
Datasheet
Recommended CDKL5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349001
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No.
ABIN6699778
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CDKL5 products
: "CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons." in: Nature cell biology, Vol. 14, Issue 9, pp. 911-23, (2012) (PubMed).: "Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation." in: American journal of human genetics, Vol. 72, Issue 6, pp. 1401-11, (2003) (PubMed).
: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).
: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).
: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).
: "Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8361-4, (1990) (PubMed).
Synonyms and alternative names related to CDKL5
cyclin dependent kinase like 5 (CDKL5), cyclin dependent kinase like 5 (cdkl5), cyclin-dependent kinase-like 5 (Cdkl5), BC038161, EIEE2, issx, ISSX, stk9, STK9, Stk9Protein level used designations for CDKL5
- cyclin-dependent kinase-like 5
- cyclin-dependent kinase-like 5-like
- cyclin dependent kinase 5 transcript
- serine/threonine kinase 9
- serine/threonine-protein kinase 9
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