CDK7 Products
(Cyclin-Dependent Kinase 7 (CDK7))
Categories
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008].
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Featured CDK7 Categories
CDK7 Antibodies
High quality antibodies with extensive validation data.
CDK7 ELISA Kits
Reliable ELISA kits for a wide range of species.
CDK7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDK7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3022405
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), DB
Validations
- (4)
Cat. No.
ABIN389541
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (4)
Cat. No.
ABIN514290
Quantity
100 μg
Datasheet
Datasheet
Recommended CDK7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966173
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380387
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN778532
Quantity
96 tests
Datasheet
Datasheet
Recommended CDK7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348979
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348981
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395140
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CDK7 products
: "Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2." in: PLoS ONE, Vol. 9, Issue 10, pp. e109170, (2014) (PubMed).: "Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation." in: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38755-66, (2012) (PubMed).
: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).
: "Cell cycle control of embryonic stem cells." in: Stem cell reviews, Vol. 1, Issue 2, pp. 131-8, (2006) (PubMed).
: "Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases." in: Cancer research, Vol. 66, Issue 21, pp. 10253-7, (2006) (PubMed).
: "Secrets of a double agent: CDK7 in cell-cycle control and transcription." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5171-80, (2005) (PubMed).
: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).
: "The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H." in: Oncogene, Vol. 21, Issue 33, pp. 5031-7, (2002) (PubMed).
: "Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr." in: Biochemical and biophysical research communications, Vol. 298, Issue 1, pp. 17-23, (2002) (PubMed).
: "Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex." in: The Journal of biological chemistry, Vol. 274, Issue 19, pp. 13162-6, (1999) (PubMed).
Synonyms and alternative names related to CDK7
cyclin dependent kinase 7 (CDK7), cyclin-dependent kinase 7 (Cdk7), Cyclin-dependent kinase 7 (Cdk7), cyclin-dependent kinase 7 L homeolog (cdk7.L), cyclin-dependent kinase 7 (cdk7), cyclin dependent kinase 7 (Cdk7), AI323415, AI528512, C230069N13, CAK1, cak1, CD 7, cdk-7, CDK7, cdk7, CDKN7, Cdkn7, cdkn7, CG3319, Crk4, dCdk7, DmCDK7, DmCdk7, Dmcdk7, Dmel\\CG3319, DmMO15, DmMo15, HCAK, MO15, Mo15, p39MO15, p39mo15, p40MO15, p40[MO15], STK1, stk1, zgc:85821Protein level used designations for CDK7
- 39 KDa protein kinase
- CAK
- CDK-activating kinase 1
- TFIIH basal transcription factor complex kinase subunit
- cell division protein kinase 7
- cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
- homolog of Xenopus MO15 Cdk-activating kinase
- kinase subunit of CAK
- p39 Mo15
- protein kinase
- serine/threonine kinase stk1
- serine/threonine protein kinase 1
- serine/threonine protein kinase MO15
- serine/threonine-protein kinase 1
- 39 kDa protein kinase
- CDK-activating kinase
- CR4 protein kinase
- CRK4 PK (CDC2-related-kinase-4 protein kinase)
- P39 Mo15
- cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
- protein-tyrosine kinase MPK-7
- 39 protein kinase
- cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase)
- CG3319-PA
- Cdk7-PA
- Mo15
- 40 kDa protein kinase
- CDC2/CDK2,4-activating kinase
- P40 MO15
- cyclin-dependent kinase 7 (MO15, cdk-activating kinase)
- cell division protein kinase 7-like protein
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