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CDC7 Products

(Cell Division Cycle 7 (CDC7))

Categories

This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008].

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Featured CDC7 Categories

CDC7 Antibodies

High quality antibodies with extensive validation data.

CDC7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDC7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7147293
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN1882165
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN6260691
Quantity 100 μL
Datasheet Datasheet

Recommended CDC7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228017
Quantity 96 tests
Datasheet Datasheet

Recommended CDC7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348867
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3091397
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120202
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CDC7 products

Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).

Kitamura, Fukatsu, Kakusho, Cho, Taniyama, Yamazaki, Toh, Yanagi, Arai, Chang, Masai: "Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition." in: The Journal of biological chemistry, Vol. 286, Issue 26, pp. 23031-43, (2011) (PubMed).

Montagnoli, Bosotti, Villa, Rialland, Brotherton, Mercurio, Berthelsen, Santocanale: "Drf1, a novel regulatory subunit for human Cdc7 kinase." in: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).

Hess, Drong, Weiland, Slightom, Sclafani, Hollingsworth: "A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines." in: Gene, Vol. 211, Issue 1, pp. 133-40, (1998) (PubMed).

Jiang, Hunter: "Identification and characterization of a human protein kinase related to budding yeast Cdc7p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14320-5, (1998) (PubMed).

Synonyms and alternative names related to CDC7

cell division cycle 7 (CDC7), cell division cycle 7-related protein kinase (Tsp_08585), cell division cycle 7 (Cdc7), cell division cycle 7 (S. cerevisiae) (Cdc7), AI597260, CDC7L1, Cdc7l1, HsCDC7, Hsk1, huCDC7, muCdc7

Protein level used designations for CDC7

  • cell division cycle 7-related protein kinase
  • CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1
  • CDC7-related kinase
  • cell division cycle 7 homolog
  • cell division cycle 7-like protein 1
  • cell division cycle 7-like 1
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