CDC6 Products
(Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
Categories
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008].
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Featured CDC6 Categories
CDC6 Antibodies
High quality antibodies with extensive validation data.
CDC6 ELISA Kits
Reliable ELISA kits for a wide range of species.
CDC6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDC6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, PLA
Validations
- (5)
Cat. No.
ABIN514244
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IP
Validations
- (7)
Cat. No.
ABIN2451939
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7147287
Quantity
100 μg
Datasheet
Datasheet
Recommended CDC6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380160
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended CDC6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348865
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348864
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091476
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CDC6 products
: "FOXM1 and androgen receptor co-regulate CDC6 gene transcription and DNA replication in prostate cancer cells." in: Biochimica et biophysica acta, Vol. 1839, Issue 4, pp. 297-305, (2014) (PubMed).: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).
: "Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1614-27, (2004) (PubMed).
: "Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1." in: The EMBO journal, Vol. 22, Issue 3, pp. 704-12, (2003) (PubMed).
: "Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis." in: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4250-9, (2003) (PubMed).
Synonyms and alternative names related to CDC6
cell division cycle 6 (CDC6), cell division cycle 6 (Cdc6), CDC18L, HsCDC6, HsCDC18Protein level used designations for CDC6
- CDC6 cell division cycle 6 homolog
- CDC6-related protein
- cdc18-related protein
- cell division control protein 6 homolog
- cell division cycle 6 homolog
- p62(cdc6)
- CDC18(S.pombe)
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