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CDC45 Products

(Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

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The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

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Featured CDC45 Categories

CDC45 Antibodies

High quality antibodies with extensive validation data.

CDC45 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDC45 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, IP
Validations
  • (4)
Cat. No. ABIN7147286
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN948673
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN563585
Quantity 100 μg
Datasheet Datasheet

Recommended CDC45 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228015
Quantity 96 tests
Datasheet Datasheet

Recommended CDC45 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348856
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348858
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3091474
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CDC45 products

Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).

Synonyms and alternative names related to CDC45

cell division cycle 45 (cdc45), cell division cycle 45 (CDC45), cell division cycle 45 S homeolog (cdc45.S), cell division cycle 45 (Cdc45), cell division cycle 45 L homeolog (cdc45.L), cdc45l, CDC45L, Cdc45l, cdc45l2, CDC45L2, porc-pi-1, PORC-PI-1

Protein level used designations for CDC45

  • CDC45 cell division cycle 45 homolog
  • cell division cycle 45 homolog
  • CDC45 cell division cycle 45-like
  • CDC45-related protein
  • cell division control protein 45 homolog
  • cell division cycle 45-like 2
  • human CDC45
  • PORC-PI-1
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