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CDC37 Products

(Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008].

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Featured CDC37 Categories

CDC37 Antibodies

High quality antibodies with extensive validation data.

CDC37 ELISA Kits

Reliable ELISA kits for a wide range of species.

CDC37 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDC37 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (5)
Cat. No. ABIN5542606
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN564833
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256126
Quantity 100 μL
Datasheet Datasheet

Recommended CDC37 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380453
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730659
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730658
Quantity 96 tests
Datasheet Datasheet

Recommended CDC37 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348819
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934995
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320133
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CDC37 products

Huang, Ye, Zhang, Wu, Zhang, Xu, Zheng: "FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation." in: Molecular cancer, Vol. 13, pp. 150, (2014) (PubMed).

Cheng, Zhao, Wang, Lu, Wang, Wang, Yao: "The effect of 5'-adenylic acid on hepatic proteome of mice radiated by 60Co γ-ray." in: International journal of molecular sciences, Vol. 15, Issue 1, pp. 186-202, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Lange, Rebollo, Herold, González: "Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes." in: The EMBO journal, Vol. 21, Issue 20, pp. 5364-74, (2002) (PubMed).

Grammatikakis, Lin, Grammatikakis, Tsichlis, Cochran: "p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function." in: Molecular and cellular biology, Vol. 19, Issue 3, pp. 1661-72, (1999) (PubMed).

Stepanova, Leng, Parker, Harper: "Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4." in: Genes & development, Vol. 10, Issue 12, pp. 1491-502, (1996) (PubMed).

Dai, Kobayashi, Beach: "Physical interaction of mammalian CDC37 with CDK4." in: The Journal of biological chemistry, Vol. 271, Issue 36, pp. 22030-4, (1996) (PubMed).

Reed: "The selection of S. cerevisiae mutants defective in the start event of cell division." in: Genetics, Vol. 95, Issue 3, pp. 561-77, (1981) (PubMed).

Synonyms and alternative names related to CDC37

CG12019 gene product from transcript CG12019-RA (Cdc37), cell division cycle 37 homolog (Cdc37), Hsp90 co-chaperone Cdc37 (cdc37), Hsp90 co-chaperone Cdc37 (AFUA_4G10010), Cdc37p (CDC37), cell division cycle 37 (CDC37), cell division cycle 37 (Cdc37), Afu4g10010, cdc37, CG12019, CPDR-1, CPDR-2, Dmel\\CG12019, DROCPDR, E(sev)3B, p50, P50CDC37, p50Cdc37

Protein level used designations for CDC37

  • CG12019-PA
  • Cdc37-PA
  • cdc37 protein
  • hsp90 co-chaperone Cdc37
  • Hsp90 co-chaperone Cdc37
  • hypothetical protein
  • CDC37 (cell division cycle 37, S. cerevisiae, homolog)
  • CDC37 cell division cycle 37 homolog
  • cell division cycle 37 homolog
  • hsp90 chaperone protein kinase-targeting subunit
  • CDC37 (cell division cycle 37 S. cerevisiae homolog)
  • p50Cdc37
  • CDC37 cell division cycle 37 protein
  • CDC37 homolog
  • cell division cycle 37 protein
  • cell division cycle control protein 37
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