CDC25B Products
(Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
Categories
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].
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Featured CDC25B Categories
CDC25B Antibodies
High quality antibodies with extensive validation data.
CDC25B ELISA Kits
Reliable ELISA kits for a wide range of species.
CDC25B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDC25B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN756967
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN756982
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256270
Quantity
100 μL
Datasheet
Datasheet
Recommended CDC25B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380386
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380112
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882277
Quantity
96 tests
Datasheet
Datasheet
Recommended CDC25B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348794
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348796
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401014
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CDC25B products
: "The BET bromodomain inhibitor JQ1 radiosensitizes non-small cell lung cancer cells by upregulating p21." in: Cancer letters, Vol. 391, pp. 141-151, (2017) (PubMed).: "Conformational flexibility of the complete catalytic domain of Cdc25B phosphatases." in: Proteins, Vol. 84, Issue 11, pp. 1567-1575, (2016) (PubMed).
: "IFI27, a novel epidermal growth factor-stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes." in: Cell proliferation, (2015) (PubMed).
: "Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B." in: Scientific reports, Vol. 5, pp. 16173, (2015) (PubMed).
: "Ser149 is another potential PKA phosphorylation target of Cdc25B in G2/M transition of fertilized mouse eggs." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10356-66, (2011) (PubMed).
: "Cdc25A and cdc25B expression in malignant lymphoma of the thyroid: correlation with histological subtypes and cell proliferation." in: International journal of molecular medicine, Vol. 13, Issue 3, pp. 431-5, (2004) (PubMed).
: "Nuclear export signal in CDC25B." in: Biochemical and biophysical research communications, Vol. 316, Issue 1, pp. 226-32, (2004) (PubMed).
: "Coordinate expression of Cdc25B and ER-alpha is frequent in low-grade endometrioid endometrial carcinoma but uncommon in high-grade endometrioid and nonendometrioid carcinomas." in: Cancer research, Vol. 63, Issue 19, pp. 6195-9, (2003) (PubMed).
Synonyms and alternative names related to CDC25B
cell division cycle 25B (cdc25b), cell division cycle 25B (CDC25B), cell division cycle 25B (Cdc25b), AI604853, CDC25BProtein level used designations for CDC25B
- cell division cycle 25 homolog B
- cell division cycle 25 homolog B (S. pombe)
- M-phase inducer phosphatase 2-like
- m-phase inducer phosphatase 2-like
- cell division cycle 25B
- M-phase inducer phosphatase 2
- dual specificity phosphatase Cdc25B
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