CD97 Products
(CD97)
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This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011].
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Featured CD97 Categories
CD97 Antibodies
High quality antibodies with extensive validation data.
CD97 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD97 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD97 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC, Neut
Validations
- (6)
Cat. No.
ABIN7193255
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN741495
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN560261
Quantity
100 μg
Datasheet
Datasheet
Recommended CD97 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965617
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965616
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6720027
Quantity
1 kit
Datasheet
Datasheet
Recommended CD97 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348745
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348744
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330008
Quantity
2 μg
Datasheet
Datasheet
Latest Publications for our CD97 products
: "Role of CD97 small isoform in human cervical carcinoma." in: International journal of experimental pathology, Vol. 100, Issue 1, pp. 19-24, (2019) (PubMed).: "Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170027, (2017) (PubMed).
: "Skeletal muscle expression of the adhesion-GPCR CD97: CD97 deletion induces an abnormal structure of the sarcoplasmatic reticulum but does not impair skeletal muscle function." in: PLoS ONE, Vol. 9, Issue 6, pp. e100513, (2014) (PubMed).
: "Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3740-8, (2013) (PubMed).
: "The invasion and metastasis promotion role of CD97 small isoform in gastric carcinoma." in: PLoS ONE, Vol. 7, Issue 6, pp. e39989, (2012) (PubMed).
: "Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions." in: PLoS ONE, Vol. 5, Issue 1, pp. e8507, (2010) (PubMed).
: "Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6574-83, (2008) (PubMed).
: "Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97." in: Infection and immunity, Vol. 75, Issue 3, pp. 1144-53, (2007) (PubMed).
: "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 22023-32, (2007) (PubMed).
: "Individual cell-based models of tumor-environment interactions: Multiple effects of CD97 on tumor invasion." in: The American journal of pathology, Vol. 169, Issue 5, pp. 1802-11, (2006) (PubMed).
Synonyms and alternative names related to CD97
adhesion G protein-coupled receptor E5 (Adgre5), adhesion G protein-coupled receptor E5 (ADGRE5), AA409984, TM7LN1Protein level used designations for CD97
- EGF-TM7 receptor
- CD97 antigen
- leukocyte antigen CD97
- seven transmembrane helix receptor
- seven-span transmembrane protein
- seven-transmembrane, heterodimeric receptor associated with inflammation
- CD97 large isoform
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