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CD94 Products

(Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

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Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured CD94 Categories

CD94 Antibodies

High quality antibodies with extensive validation data.

CD94 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD94 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (5)
Cat. No. ABIN3022763
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN969031
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7439108
Quantity 100 μL
Datasheet Datasheet

Recommended CD94 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730739
Quantity 96 tests
Datasheet Datasheet

Recommended CD94 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274271
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274272
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308894
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CD94 products

Nachmani, Zimmermann, Oiknine Djian, Weisblum, Livneh, Khanh Le, Galun, Horejsi, Isakov, Shomron, Wolf, Hengel, Mandelboim: "MicroRNA editing facilitates immune elimination of HCMV infected cells." in: PLoS pathogens, Vol. 10, Issue 2, pp. e1003963, (2014) (PubMed).

Böttger, Multhoff, Kun, Esen: "Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70." in: PLoS ONE, Vol. 7, Issue 3, pp. e33774, (2012) (PubMed).

Angelini, Zambello, Galandrini, Diamantini, Placido, Micucci, Poccia, Semenzato, Borsellino, Santoni, Battistini: "NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease." in: Journal of leukocyte biology, Vol. 89, Issue 1, pp. 75-84, (2011) (PubMed).

Yu, Mao, Wei, Hughes, Zhang, Park, Liu, McClory, Marcucci, Trotta, Caligiuri: "CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets." in: Blood, Vol. 115, Issue 2, pp. 274-81, (2010) (PubMed).

Hughes, Becknell, McClory, Briercheck, Freud, Zhang, Mao, Nuovo, Yu, Caligiuri: "Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22." in: Blood, Vol. 113, Issue 17, pp. 4008-10, (2009) (PubMed).

Chattopadhyay, ORourke, Cone: "Implication for the CD94/NKG2A-Qa-1 system in the generation and function of ocular-induced splenic CD8+ regulatory T cells." in: International immunology, Vol. 20, Issue 4, pp. 509-16, (2008) (PubMed).

Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: "Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia." in: Leukemia, Vol. 22, Issue 9, pp. 1778-81, (2008) (PubMed).

Masilamani, Narayanan, Prieto, Borrego, Coligan: "Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 6, pp. 1019-34, (2008) (PubMed).

Hallermalm, Seki, De Geer, Motyka, Bleackley, Jager, Froelich, Kiessling, Levitsky, Levitskaya: "Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3766-74, (2008) (PubMed).

Ayach, Yoshimitsu, Dawood, Sun, Arab, Chen, Higuchi, Siatskas, Lee, Lim, Zhang, Cukerman, Stanford, Medin, Liu: "Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 7, pp. 2304-9, (2006) (PubMed).

Synonyms and alternative names related to CD94

killer cell lectin like receptor D1 (KLRD1), killer cell lectin-like receptor subfamily D, member 1 (KLRD1), killer cell lectin-like receptor, subfamily D, member 1 (Klrd1), killer cell lectin like receptor D1 (Klrd1), CD94, Cd94, CD94-B

Protein level used designations for CD94

  • CD94 antigen
  • KP43
  • NK cell receptor
  • natural killer cells antigen CD94
  • killer cell lectin-like receptor family D member 1
  • killer cell lectin-like receptor subfamily D member 1
  • Killer cell lectin-like receptor subfamily D member 1
  • CD94 antigen (located within the rat natural killer gene complex)
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