CD86 Products
(CD86)
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This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
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Featured CD86 Categories
CD86 Antibodies
High quality antibodies with extensive validation data.
CD86 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD86 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD86 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
FACS, WB, ELISA, IHC (fro), IHC (p), ICC, IF (cc), IF (p)
Validations
- (12)
- (5)
Cat. No.
ABIN736701
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7440113
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IP, IHC (fro)
Validations
- (7)
- (4)
Cat. No.
ABIN302084
Quantity
0.1 mg
Datasheet
Datasheet
Recommended CD86 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965611
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967697
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965610
Quantity
96 tests
Datasheet
Datasheet
Recommended CD86 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273897
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273898
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273896
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD86 products
: "Virus-induced senescence is a driver and therapeutic target in COVID-19. ..." in: Nature, Vol. 599, Issue 7884, pp. 283-289, (2021) (PubMed).: "Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology." in: Neurobiology of disease, Vol. 134, pp. 104636, (2020) (PubMed).
: "A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope." in: mAbs, Vol. 12, Issue 1, pp. 1725365, (2020) (PubMed).
: "Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts." in: eLife, Vol. 9, (2020) (PubMed).
: "Toll-Like Receptor 2-Mediated Autophagy Promotes Microglial Cell Death by Modulating the Microglial M1/M2 Phenotype." in: Inflammation, Vol. 43, Issue 2, pp. 701-711, (2020) (PubMed).
: "TSLP promote M2 macrophages polarization and cardiac healing after myocardial infarction." in: Biochemical and biophysical research communications, Vol. 516, Issue 2, pp. 437-444, (2019) (PubMed).
: "Preventing the Solid Cancer Progression via Release of Anticancer-Cytokines in Co-Culture with Cold Plasma-Stimulated Macrophages." in: Cancers, Vol. 11, Issue 6, (2019) (PubMed).
: "Comparison of the therapeutic effect of amniotic fluid stem cells and their exosomes on monoiodoacetate-induced animal model of osteoarthritis." in: BioFactors (Oxford, England), (2019) (PubMed).
: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).
: "Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules." in: NPJ vaccines, Vol. 4, pp. 9, (2019) (PubMed).
Synonyms and alternative names related to CD86
CD86 molecule (CD86), CD86 antigen (Cd86), CD86 molecule (Cd86), integrin subunit alpha 2b (Itga2b), B7, B7-2, B7.2, B70, Cd28l2, CD28LG2, CLS1, ETC-1, LAB72, Ly-58, Ly58, MB7, MB7-2, TS/A-2Protein level used designations for CD86
- B-lymphocyte activation antigen B7-2
- BU63
- CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
- CTLA-4 counter-receptor B7.2
- FUN-1
- T-lymphocyte activation antigen CD86
- activation B7-2 antigen
- early T cell costimulatory molecule-1
- early T-cell costimulatory molecule 1
- cd86 antigen
- membrane glycoprotein
- co-stimulatory molecule B7-2
- costimulatory molecule
- B7-2 protein
- CD86 antigen
- CD86/B7-2 costimulatory molecule
- B7-1 costimulatory molecule
- integrin alpha 2b (Cd41b)
- integrin alpha-IIb
- integrin, alpha 2B
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