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CD82 Products

(CD82)

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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured CD82 Categories

CD82 Antibodies

High quality antibodies with extensive validation data.

CD82 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD82 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD82 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN390184
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), IP, ICC
Validations
  • (6)
  • (3)
Cat. No. ABIN1043024
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), IP, ICC, Func
Validations
  • (6)
  • (3)
Cat. No. ABIN2749189
Quantity 0.1 mg
Datasheet Datasheet

Recommended CD82 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973426
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951619
Quantity 96 tests
Datasheet Datasheet

Recommended CD82 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348712
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7319825
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317388
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CD82 products

Karam, Blanchet, Vivès, Boisguérin, Boudehen, Kremer, Daher: "Mycobacterium abscessus alkyl hydroperoxide reductase C promotes cell invasion by binding to tetraspanin CD81." in: iScience, Vol. 26, Issue 2, pp. 106042, (2023) (PubMed).

Xu, Shen, Zhu, Lu, Zhang, Luo, Wu: "Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression." in: OncoTargets and therapy, Vol. 10, pp. 1827-1834, (2017) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Dráberová, DAgostino, Caracciolo, Sládková, Sulimenko, Sulimenko, Sobol, Maounis, Tzelepis, Mahera, K?en, Legido, Giordano, Mörk, Hozák, Dráber, Katsetos: "Overexpression and Nucleolar Localization of ?-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 7, pp. 723-42, (2015) (PubMed).

Levy, Spahis, Garofalo, Marcil, Montoudis, Sinnet, Sanchez, Peretti, Beaulieu, Sane: "Sar1b transgenic male mice are more susceptible to high-fat diet-induced obesity, insulin insensitivity and intestinal chylomicron overproduction." in: The Journal of nutritional biochemistry, Vol. 25, Issue 5, pp. 540-8, (2014) (PubMed).

Li, Hou, Shao, Tang, Li: "The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy." in: Biology of reproduction, Vol. 82, Issue 5, pp. 968-79, (2010) (PubMed).

Gellersen, Briese, Oberndörfer, Redlin, Samalecos, Richter, Löning, Schulte, Bamberger: "Expression of the metastasis suppressor KAI1 in decidual cells at the human maternal-fetal interface: Regulation and functional implications." in: The American journal of pathology, Vol. 170, Issue 1, pp. 126-39, (2007) (PubMed).

Tohami, Drucker, Shapiro, Radnay, Lishner: "Overexpression of tetraspanins affects multiple myeloma cell survival and invasive potential." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 3, pp. 691-9, (2007) (PubMed).

Jee, Park, Surendran, Lee, Han, Kim, Lim: "KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line." in: Biochemical and biophysical research communications, Vol. 342, Issue 2, pp. 655-61, (2006) (PubMed).

Park, Tait, Kawasaki, Rowley, Mackay: "Closer association of IA-2 humoral autoreactivity with HLA DR3/4 than DQB1*0201/*0302 in Korean T1D patients." in: Annals of the New York Academy of Sciences, Vol. 1037, pp. 104-9, (2005) (PubMed).

Synonyms and alternative names related to CD82

CD82 antigen (Cd82), CD82 molecule (CD82), Cd82 molecule (Cd82), 4F9, AA682076, AL023070, C33, GR15, IA4, Kai1, KAI1, R2, SAR2, ST6, Tspan27, TSPAN27

Protein level used designations for CD82

  • C33 antigen
  • inducible membrane protein R2
  • kangai 1 (suppression of tumorigenicity 6, prostate)
  • metastasis suppressor Kangai-1 homolog
  • CD82 antigen
  • kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
  • metastasis suppressor Kangai-1
  • tetraspanin-27
  • tspan-27
  • CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4))
  • CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
  • Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen
  • Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
  • kangai 1 (suppression of tumorigenicity 6), prostate
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