CD8 Products
(CD8)
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Featured CD8 Categories
CD8 Antibodies
High quality antibodies with extensive validation data.
CD8 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, IHC (fro), WB, ELISA, IHC (p), IF (cc), IF (p)
Validations
- (26)
- (7)
Cat. No.
ABIN671391
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (4)
- (3)
Cat. No.
ABIN94235
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3030432
Quantity
100 μg
Datasheet
Datasheet
Recommended CD8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975284
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965606
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962971
Quantity
96 tests
Datasheet
Datasheet
Recommended CD8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7013442
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN6973025
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2713779
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CD8 products
: "Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair." in: Scientific reports, Vol. 7, Issue 1, pp. 14061, (2019) (PubMed).: "Expression patterns of programmed death-1 and programmed death-1 ligand-1 on T cells in gastric cancer." in: Oncology letters, Vol. 18, Issue 3, pp. 2661-2669, (2019) (PubMed).
: "A new laboratory-based algorithm to predict microvascular invasion and survival in patients with hepatocellular carcinoma." in: International journal of surgery (London, England), Vol. 57, pp. 45-53, (2018) (PubMed).
: "Black tea and D. candidum extracts play estrogenic activity via estrogen receptor α-dependent signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 114-125, (2018) (PubMed).
: "Induced global deletion of glucocorticoid receptor impairs fracture healing." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 4, pp. 2235-2245, (2018) (PubMed).
: "Acute Renal Graft-Versus-Host Disease in a Murine Model of Allogeneic Bone Marrow Transplantation." in: Cell transplantation, Vol. 26, Issue 8, pp. 1428-1440, (2018) (PubMed).
: "SIVcpz closely related to the ancestral HIV-1 is less or non-pathogenic to humans in a hu-BLT mouse model." in: Emerging microbes & infections, Vol. 7, Issue 1, pp. 59, (2018) (PubMed).
: "The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune response." in: BMC complementary and alternative medicine, Vol. 17, Issue 1, pp. 210, (2017) (PubMed).
: "Humanized mouse model for assessing the human immune response to xenogeneic and allogeneic decellularized biomaterials." in: Biomaterials, Vol. 129, pp. 98-110, (2017) (PubMed).
: "Standardized Rat Model Testing Effects of Inflammation and Grafting on Extraction Healing." in: Journal of periodontology, Vol. 88, Issue 8, pp. 799-807, (2017) (PubMed).
Synonyms and alternative names related to CD8
CD8a molecule (CD8A), CD8, Leu2, MAL, p32Protein level used designations for CD8
- CD8 antigen, alpha polypeptide (p32)
- Leu2 T-lymphocyte antigen
- OKT8 T-cell antigen
- T cell co-receptor
- T-cell antigen Leu2
- T-cell surface glycoprotein CD8 alpha chain
- T-lymphocyte differentiation antigen T8/Leu-2
- T8 T-cell antigen
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