CD70 Products
(CD70 Molecule (CD70))
Categories
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008].
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Featured CD70 Categories
CD70 Antibodies
High quality antibodies with extensive validation data.
CD70 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD70 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD70 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3022743
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (3)
- (2)
Cat. No.
ABIN2749184
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (4)
- (2)
Cat. No.
ABIN2749173
Quantity
100 tests
Datasheet
Datasheet
Recommended CD70 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954532
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973491
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889449
Quantity
96 tests
Datasheet
Datasheet
Recommended CD70 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274227
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN6961112
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274243
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD70 products
: "Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection." in: The Journal of experimental medicine, Vol. 214, Issue 1, pp. 73-89, (2017) (PubMed).: "Insights into the molecular basis of a bispecific antibody's target selectivity." in: mAbs, Vol. 7, Issue 3, pp. 461-9, (2015) (PubMed).
: "CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants." in: Cell death & disease, Vol. 5, pp. e1035, (2014) (PubMed).
: "The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4(+) T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans." in: International immunology, Vol. 21, Issue 8, pp. 891-904, (2009) (PubMed).
: "Proliferation response of leukemic cells to CD70 ligation oscillates with recurrent remission and relapse in a low-grade lymphoma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 10, pp. 6940-7, (2005) (PubMed).
: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).
: "Enhancement of adenovirus vector entry into CD70-positive B-cell Lines by using a bispecific CD70-adenovirus fiber antibody." in: Journal of virology, Vol. 75, Issue 11, pp. 5215-21, (2001) (PubMed).
: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." in: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).
: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." in: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).
: "CD27-mediated activation of murine NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1741-5, (2000) (PubMed).
Synonyms and alternative names related to CD70
CD70 antigen (Cd70), CD70 molecule (CD70), Cd70 molecule (Cd70), Cd27l, CD27L, CD27LG, Tnfsf7, TNFSF7Protein level used designations for CD70
- CD27 ligand
- CD27-L
- Ki-24 antigen
- tumor necrosis factor (ligand) superfamily, member 7
- tumor necrosis factor ligand superfamily member 7
- CD70 antigen
- surface antigen CD70
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