CD6 Products
(CD6)
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This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Featured CD6 Categories
CD6 Antibodies
High quality antibodies with extensive validation data.
CD6 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, ELISA, ICC
Validations
- (7)
Cat. No.
ABIN5542301
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, ELISA
Validations
- (6)
Cat. No.
ABIN5542300
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
- (4)
Cat. No.
ABIN1098118
Quantity
100 μL
Datasheet
Datasheet
Recommended CD6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889385
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889429
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2708164
Quantity
96 tests
Datasheet
Datasheet
Recommended CD6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274212
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320847
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964351
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD6 products
: "CD318 is a ligand for CD6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 33, pp. E6912-E6921, (2017) (PubMed).: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." in: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).
: "CD6 synergistic co-stimulation promoting proinflammatory response is modulated without interfering with the activated leucocyte cell adhesion molecule interaction." in: Clinical and experimental immunology, Vol. 162, Issue 1, pp. 116-30, (2010) (PubMed).
: "Membrane markers of the immune cells in swine: an update." in: Veterinary research, Vol. 39, Issue 6, pp. 54, (2008) (PubMed).
: "Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4351-61, (2007) (PubMed).
: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, (2007) (PubMed).
: "CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76." in: Molecular and cellular biology, Vol. 26, Issue 17, pp. 6727-38, (2006) (PubMed).
: "Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells." in: Blood, Vol. 107, Issue 8, pp. 3212-20, (2006) (PubMed).
: "OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation." in: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 183-90, (2003) (PubMed).
Synonyms and alternative names related to CD6
CD6 antigen (Cd6), CD6 molecule (CD6), Cd6 molecule (Cd6), OX52, TP120Protein level used designations for CD6
- T-cell differentiation antigen CD6
- CD6 antigen
- T12
- CD6 antigen, Tp120
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