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CD55 Products

(Complement Decay-Accelerating Factor (CD55))

Categories

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF)\; binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured CD55 Categories

CD55 Antibodies

High quality antibodies with extensive validation data.

CD55 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD55 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD55 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (1)
  • (5)
Cat. No. ABIN560554
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (fro), ICC, IHC (p)
Validations
  • (5)
Cat. No. ABIN7431821
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN3021785
Quantity 100 μL
Datasheet Datasheet

Recommended CD55 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960664
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966026
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882227
Quantity 96 tests
Datasheet Datasheet

Recommended CD55 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274193
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274204
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274191
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD55 products

Sánchez-Adriá, Sanmartín, Prieto, Estruch, Randez-Gil: "Slt2 Is Required to Activate ER-Stress-Protective Mechanisms through TORC1 Inhibition and Hexosamine Pathway Activation." in: Journal of fungi (Basel, Switzerland), Vol. 8, Issue 2, (2022) (PubMed).

Kim, Koo, Kim, Hong, Kim, Yang, Kim: "Role of IL-1ra and Granzyme B as biomarkers in active Crohn's disease patients." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 23, Issue 2, pp. 161-166, (2018) (PubMed).

Liu, Liu, Yuan, Qing, Li, Xu, Zhu, Zhao, Jia, Pan, Guo, Zhang, Cheng, Wang, Zhao, Wei: "Generation of GTKO Diannan Miniature Pig Expressing Human Complementary Regulator Proteins hCD55 and hCD59 via T2A Peptide-Based Bicistronic Vectors and SCNT." in: Molecular biotechnology, (2018) (PubMed).

Goetzl, Schwartz, Abner, Jicha, Kapogiannis: "High complement levels in astrocyte-derived exosomes of Alzheimer disease." in: Annals of neurology, Vol. 83, Issue 3, pp. 544-552, (2018) (PubMed).

Olcina, Balanis, Kim, Aksoy, Kodysh, Thompson, Hammerbacher, Graeber, Giaccia: "Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer." in: Cell reports, Vol. 25, Issue 13, pp. 3721-3732.e6, (2018) (PubMed).

Kwon, Kim, Hwang, Kim, Kim, Kim, Lee, Im, Lee, Hwang: "Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes." in: Transgenic research, Vol. 26, Issue 1, pp. 153-163, (2018) (PubMed).

Kwon, Kim, Meyer, Di Bisceglie, Ray: "Distinct CD55 Isoform Synthesis and Inhibition of Complement-Dependent Cytolysis by Hepatitis C Virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 4, pp. 1127-36, (2017) (PubMed).

Izuhara, Tatsumi, Miyagawa, Iwai, Watanabe, Yamanaka, Katsuoka, Nagashima, Okano, Yokoo: "Generation of a felinized Swine endothelial cell line by expression of feline decay-accelerating factor." in: PLoS ONE, Vol. 10, Issue 2, pp. e0117682, (2015) (PubMed).

Tam, Bidgood, McEwan, James: "Intracellular sensing of complement C3 activates cell autonomous immunity." in: Science (New York, N.Y.), Vol. 345, Issue 6201, pp. 1256070, (2014) (PubMed).

Ingham, Williams, Bate: "Glimepiride reduces CD14 expression and cytokine secretion from macrophages." in: Journal of neuroinflammation, Vol. 11, pp. 115, (2014) (PubMed).

Synonyms and alternative names related to CD55

CD55 molecule (Cromer blood group) (CD55), CD55 molecule, decay accelerating factor for complement (Cd55), CD55 molecule (Cromer blood group) (Cd55), CR, CROM, DAF, Daf, Daf-GPI, Daf1, GPI-DAF, TC

Protein level used designations for CD55

  • CD55 antigen
  • complement decay-accelerating factor
  • Cromer blood group
  • GPI anchor addition signal
  • complement decay-accelerating factor, GPI-anchored
  • complement-glycosylphosphatidylinositol
  • decay accelerating factor 1
  • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
  • decay-accelerating factor (GDab-TCS)
  • decay-accelerating factor CD55
  • decay accelarating factor 1
  • decay accelerating factor GPI-form
  • decay-accelarating factor
  • glycosylphophatidylinositol-anchored form
  • decay accelerating factor for complement
  • decay-accelerating factor 1
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