CD51 Products
(Integrin alpha V (ITGAV))
Categories
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009].
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Featured CD51 Categories
CD51 Antibodies
High quality antibodies with extensive validation data.
CD51 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD51 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD51 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN7267922
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
Cat. No.
ABIN3022888
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7445879
Quantity
100 μL
Datasheet
Datasheet
Recommended CD51 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956843
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967692
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882224
Quantity
96 tests
Datasheet
Datasheet
Recommended CD51 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1308183
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964181
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423180
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD51 products
: "Mechanically induced formation and maturation of 3D-matrix adhesions (3DMAs) in human mesenchymal stem cells." in: Biomaterials, Vol. 258, pp. 120292, (2020) (PubMed).: "Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target." in: The Journal of clinical investigation, Vol. 129, Issue 1, pp. 137-149, (2019) (PubMed).
: "GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer." in: Theranostics, Vol. 9, Issue 4, pp. 1047-1065, (2019) (PubMed).
: "β8 Integrin Mediates Pancreatic Cancer Cell Radiochemoresistance." in: Molecular cancer research : MCR, (2019) (PubMed).
: "The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation." in: Nature communications, Vol. 10, Issue 1, pp. 3181, (2019) (PubMed).
: "Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells." in: Oncotarget, Vol. 7, Issue 28, pp. 43852-43867, (2018) (PubMed).
: "cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 261, pp. 275-286, (2018) (PubMed).
: "Soluble bone-derived osteopontin promotes migration and stem-like behavior of breast cancer cells." in: PLoS ONE, Vol. 12, Issue 5, pp. e0177640, (2017) (PubMed).
: "Plasma endothelial microparticles reflect the extent of capillaroscopic alterations and correlate with the severity of skin involvement in systemic sclerosis." in: Microvascular research, Vol. 110, pp. 24-31, (2017) (PubMed).
: "Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model." in: Oncotarget, Vol. 8, Issue 65, pp. 108676-108691, (2017) (PubMed).
Synonyms and alternative names related to CD51
integrin subunit alpha V (ITGAV), integrin alpha V (Itgav), integrin subunit alpha V (Itgav), 1110004F14Rik, 2610028E01Rik, CD51, Cd51, D430040G12Rik, MSK8, VNRA, VTNRProtein level used designations for CD51
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- alphav integrin
- integrin alpha V
- integrin alpha-V
- vitronectin receptor alpha polypeptide (VNRA)
- vitronectin receptor subunit alpha
- antigen identified by monoclonal antibody L230
- integrin alphaVbeta3
- Dnmt3l-ps1 pseudogene
- alphaV integrin
- integrin alpha v
- vitronectin receptor alpha subunit
- integrin alpha V subunit
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