CD33 Products
(CD33)
Categories
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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Featured CD33 Categories
CD33 Antibodies
High quality antibodies with extensive validation data.
CD33 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD33 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD33 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p)
Validations
- (5)
- (6)
Cat. No.
ABIN687607
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA, IHC
Validations
- (2)
- (7)
Cat. No.
ABIN1724812
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440323
Quantity
100 μL
Datasheet
Datasheet
Recommended CD33 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965566
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965565
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962469
Quantity
96 tests
Datasheet
Datasheet
Recommended CD33 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274159
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275588
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274160
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD33 products
: "Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 121, pp. 70-75, (2019) (PubMed).: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." in: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).
: "In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia." in: Molecular cancer therapeutics, Vol. 15, Issue 10, pp. 2422-2431, (2016) (PubMed).
: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).
: "miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells." in: International journal of oncology, Vol. 48, Issue 4, pp. 1737-48, (2016) (PubMed).
: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." in: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, (2015) (PubMed).
: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." in: Transplantation, Vol. 99, Issue 4, pp. 668-77, (2015) (PubMed).
: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1270, (2015) (PubMed).
: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).
: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).
Synonyms and alternative names related to CD33
CD33 molecule (CD33), CD33 antigen (Cd33), CD33 molecule (Cd33), gp67, p67, SIGLEC-3, Siglec-3, SIGLEC3Protein level used designations for CD33
- CD33 antigen (gp67)
- gp67
- myeloid cell surface antigen CD33
- sialic acid binding Ig-like lectin 3
- sialic acid-binding Ig-like lectin 3
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