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CD300a Products

(CD300a (CD300A))

Categories

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Featured CD300a Categories

CD300a Antibodies

High quality antibodies with extensive validation data.

CD300a ELISA Kits

Reliable ELISA kits for a wide range of species.

CD300a Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD300a Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA
Validations
  • (3)
Cat. No. ABIN7193471
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN192408
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6260608
Quantity 100 μL
Datasheet Datasheet

Recommended CD300a ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5564600
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4885159
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385458
Quantity 96 tests
Datasheet Datasheet

Recommended CD300a Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274278
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274280
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274286
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD300a products

Larsen, Juel-Berg, Hansen, Hansen, Mills, van Ree, Rådinger, Poulsen, Jensen: "No difference in human mast cells derived from peanut allergic versus non-allergic subjects." in: Immunity, inflammation and disease, Vol. 6, Issue 4, pp. 416-427, (2019) (PubMed).

Valiate, Alvarez, Karra, Queiroz-Júnior, Amaral, Levi-Schaffer, Teixeira: "The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice." in: Journal of leukocyte biology, (2019) (PubMed).

Karra, Singh Gangwar, Shamri, Puzzovio, Cohen-Mor, Levy, Levi-Schaffer: "Leukocyte CD300a Contributes to the Resolution of Murine Allergic Inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 10, pp. 2998-3005, (2018) (PubMed).

Rozenberg, Reichman, Zab-Bar, Itan, Pasmanik-Chor, Bouffi, Qimron, Bachelet, Fulkerson, Rothenberg, Munitz: "CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production." in: Scientific reports, Vol. 7, Issue 1, pp. 5922, (2017) (PubMed).

Sabato, Verweij, Bridts, Levi-Schaffer, Gibbs, De Clerck, Schiavino, Ebo: "CD300a is expressed on human basophils and seems to inhibit IgE/Fc?RI-dependent anaphylactic degranulation." in: Cytometry. Part B, Clinical cytometry, Vol. 82, Issue 3, pp. 132-8, (2012) (PubMed).

Dimasi, Roessle, Moran, Candiano, Svergun, Biassoni: "Molecular analysis and solution structure from small-angle X-ray scattering of the human natural killer inhibitory receptor IRp60 (CD300a)." in: International journal of biological macromolecules, Vol. 40, Issue 3, pp. 193-200, (2007) (PubMed).

Alvarez, Tang, Coligan, Borrego: "The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling." in: Molecular immunology, Vol. 45, Issue 1, pp. 253-8, (2007) (PubMed).

Bachelet, Munitz, Levi-Schaffer: "Abrogation of allergic reactions by a bispecific antibody fragment linking IgE to CD300a." in: The Journal of allergy and clinical immunology, Vol. 117, Issue 6, pp. 1314-20, (2006) (PubMed).

Bachelet, Munitz, Mankutad, Levi-Schaffer: "Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process." in: The Journal of biological chemistry, Vol. 281, Issue 37, pp. 27190-6, (2006) (PubMed).

Bachelet, Munitz, Moretta, Moretta, Levi-Schaffer: "The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 7989-95, (2005) (PubMed).

Synonyms and alternative names related to CD300a

CD300 molecule like family member g (CD300LG), CD300a molecule (CD300A), CMRF35-like molecule 8 (LOC483289), CMRF35-like molecule 8 (clm8), CD300A molecule (Cd300a), Cd300a molecule (Cd300a), B230315M08Rik, CD300A, CD300L-B1, CLM-8, clm8, Clm8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, LMIR1, MAIR-I, MAIR-Ia, mcpir1, MMAC8, Pigr4

Protein level used designations for CD300a

  • CD300a molecule
  • CD300 antigen-like family member
  • CMRF35-like molecule 8
  • CD300 antigen-like family member A
  • CLM-8
  • MAIR-1
  • leukocyte mono-Ig-like receptor 1
  • mast cell-derived paired immunoglobulin-like receptor 1
  • myeloid-associated immunoglobulin-like receptor 1
  • polymeric immunoglobulin receptor 4
  • CD300a antigen
  • CMRF35H leukocyte immunoglobulin-like receptor
  • NK inhibitory receptor
  • immunoglobulin superfamily member 12
  • inhibitory receptor protein 60
  • leukocyte membrane antigen
  • immune inhibitory receptor CD300A
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