CD276 Products
(CD276)
Categories
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
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Featured CD276 Categories
CD276 Antibodies
High quality antibodies with extensive validation data.
CD276 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD276 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD276 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS, IHC, ICC
Validations
- (6)
Cat. No.
ABIN5611271
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432586
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN656709
Quantity
400 μL
Datasheet
Datasheet
Recommended CD276 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954503
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975125
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951401
Quantity
96 tests
Datasheet
Datasheet
Recommended CD276 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273959
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273948
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD276 products
: "B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression." in: Cell death & disease, Vol. 11, Issue 1, pp. 55, (2020) (PubMed).: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." in: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).
: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." in: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).
: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." in: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).
: "B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma." in: Laboratory investigation; a journal of technical methods and pathology, (2019) (PubMed).
: "B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2." in: Cell death & disease, Vol. 10, Issue 4, pp. 308, (2019) (PubMed).
: "Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent." in: Theranostics, Vol. 7, Issue 6, pp. 1463-1476, (2018) (PubMed).
: "Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0172858, (2017) (PubMed).
: "B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway." in: Journal of Cancer, Vol. 8, Issue 5, pp. 816-824, (2017) (PubMed).
: "High constitutive B7-H3 expression on human keratinocytes supports T cell immunity." in: Journal of dermatological science, Vol. 87, Issue 1, pp. 82-85, (2017) (PubMed).
Synonyms and alternative names related to CD276
CD276 molecule (CD276), CD276 molecule S homeolog (cd276.S), CD276 molecule (cd276), CD276 antigen (Cd276), Cd276 molecule (Cd276), 4Ig-B7-H3, 6030411F23Rik, AU016588, B7-H3, B7h3, B7H3, B7RP-2, sc:d0645, zgc:158279Protein level used designations for CD276
- CD276 molecule
- CD276 antigen-like
- CD276 antigen homolog
- CD276 antigen
- B7 homolog 3
- B7-H3
- costimulatory molecule
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