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CD25 Products

(Interleukin 2 Receptor, alpha (IL2RA))
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009].

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Featured CD25 Categories

CD25 Antibodies

High quality antibodies with extensive validation data.

CD25 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD25 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD25 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application FACS, WB, ELISA, IHC (p)
Validations
  • (2)
  • (1)
Cat. No. ABIN670371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, ELISA, ICC
Validations
  • (2)
  • (7)
Cat. No. ABIN1724861
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (fro), IHC (p)
Validations
  • (5)
Cat. No. ABIN7434179
Quantity 100 μL
Datasheet Datasheet

Recommended CD25 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
Cat. No. ABIN6730938
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957088
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962952
Quantity 96 tests
Datasheet Datasheet

Recommended CD25 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274206
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274199
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274200
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD25 products

Wang, Bi, Zhu, He, Lai, Xia, Cai: "IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma." in: Cancer communications (London, England), Vol. 38, Issue 1, pp. 62, (2019) (PubMed).

Garcia-Obregon, Azkargorta, Seijas, Pilar-Orive, Borrego, Elortza, Boyano, Astigarraga: "Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients." in: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, Vol. 51, Issue 4, pp. 465-472, (2018) (PubMed).

Yan, Nie, Wu, Zhang, Zhu, Zhang, Sun: "Soluble interleukin‑2 receptor as a factor associated with angiogenesis in gastric cancer." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6916-6919, (2018) (PubMed).

Samanta, Park, Ni, Li, Zahnow, Gabrielson, Pan, Semenza: "Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 6, pp. E1239-E1248, (2018) (PubMed).

Izadi, Hajizadeh-Saffar, Hadjati, Habibi-Anbouhi, Ghanian, Sadeghi-Abandansari, Ashtiani, Samsonchi, Raoufi, Moazenchi, Izadi, Nejad, Namdari, Tahamtani, Ostad, Akbari-Javar, Baharvand: "Tolerance induction by surface immobilization of Jagged-1 for immunoprotection of pancreatic islets." in: Biomaterials, Vol. 182, pp. 191-201, (2018) (PubMed).

Kim, Kang, Choi, Joo, Kim, Song: "Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation." in: Oncotarget, Vol. 8, Issue 9, pp. 15858-15877, (2017) (PubMed).

Clement, Becerra, Yin, Zolla, Huang, Merlin, Follenzi, Shaffer, Stern, Santambrogio: "The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity." in: The Journal of biological chemistry, Vol. 291, Issue 11, pp. 5576-95, (2016) (PubMed).

Grati, Yan, Raval, Walsh, Ma, Chakchouk, Kannan-Sundhari, Mittal, Masmoudi, Blanton, Tekin, King, Yengo, Liu: "MYO3A Causes Human Dominant Deafness and Interacts with Protocadherin 15-CD2 Isoform." in: Human mutation, Vol. 37, Issue 5, pp. 481-7, (2016) (PubMed).

Gao, Camous, Lu, Lim, Larbi, Ng: "Novel inflammatory markers associated with cognitive performance: Singapore Longitudinal Ageing Studies." in: Neurobiology of aging, Vol. 39, pp. 140-6, (2016) (PubMed).

Vorselaars, van Moorsel, Zanen, Ruven, Claessen, van Velzen-Blad, Grutters: "ACE and sIL-2R correlate with lung function improvement in sarcoidosis during methotrexate therapy." in: Respiratory medicine, Vol. 109, Issue 2, pp. 279-85, (2015) (PubMed).

Synonyms and alternative names related to CD25

interleukin 2 receptor subunit alpha (IL2RA), interleukin 2 receptor subunit alpha (Il2ra), interleukin-2 receptor subunit alpha-like (LOC100222957), interleukin 2 receptor, alpha chain (Il2ra), CD25, IDDM10, IL-2RA, IL2R, Il2r, IL2RAC, Ly-43, TCGFR

Protein level used designations for CD25

  • IL-2 receptor subunit alpha
  • IL-2-RA
  • IL-2R subunit alpha
  • IL2-RA
  • TAC antigen
  • interleukin-2 receptor subunit alpha
  • p55
  • IL-2 receptor alpha subunit
  • interleukin 2 receptor, alpha chain
  • interleukin-2 receptor alpha chain
  • IL-2 alpha receptor
  • IL2 receptor alpha
  • interleukin-2 alpha receptor
  • interleukin 2 receptor alpha chain
  • interleukin-2 receptor alpha subunit
  • IL-2 Receptor alpha chain
  • interleukin 2 receptor, alpha
  • IL-2R alpha chain
  • p55 chain
  • IL-2R alpha
  • cytokine receptor
  • CD25 antigen
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